Nature Search

PTC taste blindness and the taste of caffeine

MOLLY J. HALL
LINDA M. BARTOSHUK
JOSEPH C. STEVENS
Research06 Feb 1975
Nature

Volume: 253, P: 442-443
DNMT1-mediated regulation of somatostatin-positive interneuron migration impacts cortical architecture and function

The function of DNMT1 (DNA methyltransferase 1) in these subsets of immature, migrating cortical inhibitory interneurons is not fully understood. This study shows that DNMT1 regulates cortical development by orchestrating the migration of postmitotic SST+ interneurons and their signaling to cortical progenitors, with implications for proper cortical architecture and function.

Julia Reichard
Philip Wolff
Geraldine Zimmer-Bensch
ResearchOpen Access24 Jul 2025
Nature Communications

Volume: 16, P: 1-22
Delivery of antigen-encoding plasmid DNA into the cytosol of macrophages by attenuated suicide Listeria monocytogenes

Guido Dietrich
Andreas Bubert
Werner Goebel
Research01 Feb 1998
Nature Biotechnology

Volume: 16, P: 181-185
Oncogenic activation of c-Myb by carboxyl-terminal truncation leads to decreased proteolysis by the ubiquitin-26S proteasome pathway

Juraj Bies
Linda Wolff
Research16 Jan 1997
Oncogene

Volume: 14, P: 203-212
Conservation of primary structure in 16S ribosomal RNA

CARL R. WOESE
GEORGE E. Fox
DAVID STAHL
Research06 Mar 1975
Nature

Volume: 254, P: 83-86
Deregulated c-Myb expression in murine myeloid leukemias prevents the up-regulation of p15^INK4b normally associated with differentiation

Martina Schmidt
Richard Koller
Linda Wolff
Research12 Oct 2001
Oncogene

Volume: 20, P: 6205-6214
Common variants in 22 loci are associated with QRS duration and cardiac ventricular conduction

Nona Sotoodehnia and colleagues report a meta-analysis of 14 genome-wide association studies for QRS interval, an electrocardiogram measurement of cardiac ventricular conduction. They identify 22 loci associated with QRS duration.

Nona Sotoodehnia
Aaron Isaacs
Dan E Arking
Research14 Nov 2010
Nature Genetics

Volume: 42, P: 1068-1076
Cellular hormetic response to 27-hydroxycholesterol promotes neuroprotection through AICD induction of MAST4 abundance and kinase activity

Brendan Gongol
Traci L. Marin
Salvador Soriano
ResearchOpen Access24 Oct 2017
Scientific Reports

Volume: 7, P: 1-11
Towards establishing a fungal economics spectrum in soil saprobic fungi

Challenges in obtaining empirical trait data hinder the development of trait-based frameworks for soil microbes. Here, the authors analyse traits of saprobic fungal isolates from a grassland site to propose a fungal economics spectrum, suggesting a general trait framework for soil fungi.

Tessa Camenzind
Carlos A. Aguilar-Trigueros
Matthias C. Rillig
ResearchOpen Access18 Apr 2024
Nature Communications

Volume: 15, P: 1-13
144 COMPARISON OF THE SENSITIVITY OF M-MODE CONTRAST AND DOPPLER CONTRAST

Stanley J Goldberg
Lilliam M Valdes-Cruz
Linda Feldman
Research01 Apr 1981
Pediatric Research

Volume: 15, P: 463
Morphology of Immunomodulation in Breast Cancer Tumor Draining Lymph Nodes Depends on Stage and Intrinsic Subtype

Maximilian Seidl
Moritz Bader
Peter Bronsert
ResearchOpen Access28 Mar 2018
Scientific Reports

Volume: 8, P: 1-12
Hyperphosphorylation and increased proteolytic breakdown of c-Myb induced by the inhibition of Ser/Thr protein phosphatases

Juraj Bies
Sona Feiková
Linda Wolff
Research01 Jun 2000
Oncogene

Volume: 19, P: 2846-2854
Adaptive mutations in NEP compensate for defective H5N1 RNA replication in cultured human cells

Adaptive mutations in the avian influenza virus permit replication in mammals but how these mutations enable this effect is unclear. In this study, mutations found in the nuclear export protein of human isolates of H5N1 are shown to enhance the replication of viral RNA in human cells in culture.

Benjamin Mänz
Linda Brunotte
Martin Schwemmle
Research01 May 2012
Nature Communications

Volume: 3, P: 1-11
Further Evidence for Genetic Heterogeneity in Familial Hemophagocytic Lymphohistiocytosis (FHLH)

Gail E Graham
Lisa M Graham
R Maarten Egeler
Research01 Aug 2000
Pediatric Research

Volume: 48, P: 227-232
Neoadjuvant Therapy in Rectal Cancer - Biobanking of Preoperative Tumor Biopsies

Peter Jo
Manuel Nietert
Jochen Gaedcke
ResearchOpen Access18 Oct 2016
Scientific Reports

Volume: 6, P: 1-9
Hypermethylation of the Ink4b locus in murine myeloid leukemia and increased susceptibility to leukemia in p15^Ink4b-deficient mice

Linda Wolff
Matthew T Garin
Christine Perella
Research18 Dec 2003
Oncogene

Volume: 22, P: 9265-9274
Humane endpoints, defined

Animals used in biomedical research may experience pain or distress as part of the experimental protocol. By implementing humane endpoints, pain or distress can be prevented or alleviated whilst still meeting scientific aims and objectives. We invited experts from Arizona State University (Samantha Sullivan) and Loma Linda University (Obed Rutebuka), along with USDA and OLAW representatives (Louis DiVincenti and Axel Wolff), to respond to a scenario about the importance of defining humane endpoints in research protocols.

Lauren Danridge
Bill Greer
Axel Wolff
Comments & Opinion04 Jun 2024
Lab Animal

Volume: 53, P: 123-125
Comparison of hydroxyapatite and fluoride oral care gels for remineralization of initial caries: a pH-cycling study

Bennett T. Amaechi
Parveez Ahamed AbdulAzees
Joachim Enax
ResearchOpen Access22 Jul 2020
BDJ Open

Volume: 6, P: 1-7
Response and resistance to MEK inhibition in leukaemias initiated by hyperactive Ras

In human cancers with deregulated Ras signalling, including tumours that have inactivated the Nf1 tumour suppressor, the cascade comprising Raf, mitogen-activated protein kinase kinase (MEK) and extracellular signal-regulated kinase (ERK) is a therapeutic target. Here, in mice, the effects of inhibitors of MEK in a model of myeloproliferative disorder initiated by inactivating Nf1 and in a model of acute myeloid leukaemia are compared.

Jennifer O. Lauchle
Doris Kim
Kevin Shannon
Research02 Sept 2009
Nature

Volume: 461, P: 411-414
Nuclear entry of nonviral vectors

D A Dean
D D Strong
W E Zimmer
Reviews28 Apr 2005
Gene Therapy

Volume: 12, P: 881-890
Ex vivo purging by adenoviral p53 gene therapy does not affect NOD-SCID repopulating activity of human CD34⁺ cells

Manabu Hirai
Drake LaFace
James Talmadge
Research21 Dec 2001
Cancer Gene Therapy

Volume: 8, P: 936-947
Application of biological monitoring for exposure assessment following chemical incidents: A procedure for decision making

Paul T J Scheepers
Peter M J Bos
Linda Grievink
Research24 Mar 2010
Journal of Exposure Science & Environmental Epidemiology

Volume: 21, P: 247-261
Consistent inactivation of p19^Arf but not p15^Ink4b in murine myeloid cells transformed in vivo by deregulated c-Myc

Peter Haviernik
Martina Schmidt
Linda Wolff
Research18 Mar 2003
Oncogene

Volume: 22, P: 1600-1610
Epidemiology of 7375 children and adolescents hospitalized with COVID-19 in Germany, reported via a prospective, nationwide surveillance study in 2020–2022

Maren Doenhardt
Markus Hufnagel
Ulrich Zügge
ResearchOpen Access02 Jan 2024
Scientific Reports

Volume: 14, P: 1-15
Male-specific late effects in adult hematopoietic cell transplantation recipients: a systematic review from the Late Effects and Quality of Life Working Committee of the Center for International Blood and Marrow Transplant Research and Transplant Complications Working Party of the European Society of Blood and Marrow Transplantation

Rachel Phelan
Annie Im
André Tichelli
Research06 May 2022
Bone Marrow Transplantation

Volume: 57, P: 1150-1163
Guidelines for the testing and reporting of cytogenetic results for risk stratification of multiple myeloma: a report of the Cancer Genomics Consortium Plasma Cell Neoplasm Working Group

Xinyan Lu
Erica F. Andersen
Linda B. Baughn
ReviewsOpen Access18 Jun 2025
Blood Cancer Journal

Volume: 15, P: 1-10
Maintenance of the functional integrity of mouse hematopoiesis by EED and promotion of leukemogenesis by EED haploinsufficiency

Kenichiro Ikeda
Takeshi Ueda
Hiroaki Honda
ResearchOpen Access19 Jul 2016
Scientific Reports

Volume: 6, P: 1-13
Pediatric SARS-CoV-2 long term outcomes study (PECOS): cross sectional analysis at baseline

Gina A. Montealegre Sanchez
Lauren E. Arrigoni
Roberta L. DeBiasi
ResearchOpen Access18 Dec 2024
Pediatric Research

Volume: 98, P: 541-550
The Exome Clinic and the role of medical genetics expertise in the interpretation of exome sequencing results

Dustin Baldridge
Jennifer Heeley
Marwan Shinawi
Research02 Mar 2017
Genetics in Medicine

Volume: 19, P: 1040-1048
Technical standards and guidelines: Venous thromboembolism (Factor V Leiden and prothrombin 20210G>A testing): A disease-specific supplement to the standards and guidelines for clinical genetics laboratories

Elaine B Spector
Wayne W Grody
C Sue Richards
Research01 Jul 2005
Genetics in Medicine

Volume: 7, P: 444-453
HTLV-I Tax transrepresses the human c-Myb promoter independently of its interaction with CBP or p300

Christophe Nicot
Renaud Mahieux
Genoveffa Franchini
Research15 May 2000
Oncogene

Volume: 19, P: 2155-2164
Distal regulation of c-myb expression during IL-6-induced differentiation in murine myeloid progenitor M1 cells

Junfang Zhang
Bingshe Han
Linda Wolff
ResearchOpen Access08 Sept 2016
Cell Death & Disease

Volume: 7, P: e2364
Chromosomal microarray analysis, including constitutional and neoplastic disease applications, 2021 revision: a technical standard of the American College of Medical Genetics and Genomics (ACMG)

Lina Shao
Yassmine Akkari
Fady M. Mikhail
Reviews15 Jun 2021
Genetics in Medicine

Volume: 23, P: 1818-1829
Standards and Guidelines for CFTR Mutation Testing

Carolyn Sue Richards
Linda A Bradley
Michael S Watson
Research01 Sept 2002
Genetics in Medicine

Volume: 4, P: 379-391
Technical laboratory standards for interpretation and reporting of acquired copy-number abnormalities and copy-neutral loss of heterozygosity in neoplastic disorders: a joint consensus recommendation from the American College of Medical Genetics and Genomics (ACMG) and the Cancer Genomics Consortium (CGC)

Fady M. Mikhail
Jaclyn A. Biegel
Gordana Raca
Reviews29 May 2019
Genetics in Medicine

Volume: 21, P: 1903-1916
American College of Medical Genetics and Genomics technical standards and guidelines: microarray analysis for chromosome abnormalities in neoplastic disorders

Linda D. Cooley
Matthew Lebo
Daynna J. Wolff
Research25 Apr 2013
Genetics in Medicine

Volume: 15, P: 484-494

Search

PTC taste blindness and the taste of caffeine

DNMT1-mediated regulation of somatostatin-positive interneuron migration impacts cortical architecture and function

Delivery of antigen-encoding plasmid DNA into the cytosol of macrophages by attenuated suicide Listeria monocytogenes

Oncogenic activation of c-Myb by carboxyl-terminal truncation leads to decreased proteolysis by the ubiquitin-26S proteasome pathway

Conservation of primary structure in 16S ribosomal RNA

Deregulated c-Myb expression in murine myeloid leukemias prevents the up-regulation of p15^INK4b normally associated with differentiation

Common variants in 22 loci are associated with QRS duration and cardiac ventricular conduction

Cellular hormetic response to 27-hydroxycholesterol promotes neuroprotection through AICD induction of MAST4 abundance and kinase activity

Towards establishing a fungal economics spectrum in soil saprobic fungi

144 COMPARISON OF THE SENSITIVITY OF M-MODE CONTRAST AND DOPPLER CONTRAST

Morphology of Immunomodulation in Breast Cancer Tumor Draining Lymph Nodes Depends on Stage and Intrinsic Subtype

Hyperphosphorylation and increased proteolytic breakdown of c-Myb induced by the inhibition of Ser/Thr protein phosphatases

Adaptive mutations in NEP compensate for defective H5N1 RNA replication in cultured human cells

Further Evidence for Genetic Heterogeneity in Familial Hemophagocytic Lymphohistiocytosis (FHLH)

Neoadjuvant Therapy in Rectal Cancer - Biobanking of Preoperative Tumor Biopsies

Hypermethylation of the Ink4b locus in murine myeloid leukemia and increased susceptibility to leukemia in p15^Ink4b-deficient mice

Humane endpoints, defined

Comparison of hydroxyapatite and fluoride oral care gels for remineralization of initial caries: a pH-cycling study

Response and resistance to MEK inhibition in leukaemias initiated by hyperactive Ras

Nuclear entry of nonviral vectors

Ex vivo purging by adenoviral p53 gene therapy does not affect NOD-SCID repopulating activity of human CD34⁺ cells

Application of biological monitoring for exposure assessment following chemical incidents: A procedure for decision making

Consistent inactivation of p19^Arf but not p15^Ink4b in murine myeloid cells transformed in vivo by deregulated c-Myc

Epidemiology of 7375 children and adolescents hospitalized with COVID-19 in Germany, reported via a prospective, nationwide surveillance study in 2020–2022

Guidelines for the testing and reporting of cytogenetic results for risk stratification of multiple myeloma: a report of the Cancer Genomics Consortium Plasma Cell Neoplasm Working Group

Maintenance of the functional integrity of mouse hematopoiesis by EED and promotion of leukemogenesis by EED haploinsufficiency

Pediatric SARS-CoV-2 long term outcomes study (PECOS): cross sectional analysis at baseline

The Exome Clinic and the role of medical genetics expertise in the interpretation of exome sequencing results

Technical standards and guidelines: Venous thromboembolism (Factor V Leiden and prothrombin 20210G>A testing): A disease-specific supplement to the standards and guidelines for clinical genetics laboratories

HTLV-I Tax transrepresses the human c-Myb promoter independently of its interaction with CBP or p300

Distal regulation of c-myb expression during IL-6-induced differentiation in murine myeloid progenitor M1 cells

Chromosomal microarray analysis, including constitutional and neoplastic disease applications, 2021 revision: a technical standard of the American College of Medical Genetics and Genomics (ACMG)

Standards and Guidelines for CFTR Mutation Testing

American College of Medical Genetics and Genomics technical standards and guidelines: microarray analysis for chromosome abnormalities in neoplastic disorders

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