During cortical development the first wave of oligodendrocyte precursor cells (OPCs) completely disappear by programmed cell death, so that it is presumed that this OPC population does not play a role at postnatal stages. In this study, authors use lineage tracing in different transgenic mice to show that a subpopulation of OPCs from the first wave survives at postnatal stages and display a preferential synaptic connectivity with their ontogenetically-related interneurons compared to other OPCs or interneurons
- David Orduz
- Najate Benamer
- María Cecilia Angulo