Tools to simultaneously trace multiple neuronal projections and/or profile projection neurons for multi-modal investigations are lacking. Here authors introduce Projection-TAGs, a retrograde AAV platform to enable multiplexed spatial neuroanatomical studies, high-throughput multi-modal (transcriptional, and epigenetic) profiling of projection neurons using various commercial assays.
- Lite Yang
- Fang Liu
- Vijay K. Samineni
