Nature Search

Molecular basis of ligand binding and receptor activation at the human A₃ adenosine receptor

The A3 adenosine receptor is a promising drug target for cancer, inflammation, and glaucoma. Here, authors determine atomic structures of the human A3 receptor, identifying a previously hidden binding pocket that will aid in the development of more effective A3 receptor-targeted medicines.

Liudi Zhang
Jesse I. Mobbs
David M. Thal
ResearchOpen Access18 Aug 2025
Nature Communications

Volume: 16, P: 1-19
Morphology-dependent Electrochemical Enhancements of Porous Carbon as Sensitive Determination Platform for Ascorbic Acid, Dopamine and Uric Acid

Qin Cheng
Liudi Ji
Weikang Zhang
ResearchOpen Access29 Feb 2016
Scientific Reports

Volume: 6, P: 1-8
Spontaneously established reverse electric field to enhance the performance of triboelectric nanogenerators via improving Coulombic efficiency

Performance of triboelectric nanogenerators is limited by electrostatic breakdown. Here, the spontaneously established reverse electric field is introduced to restrict the side-discharge problem caused by electrostatic breakdown, leading to a high Coulombic efficiency and enhanced output power.

Yikui Gao
Lixia He
Jie Wang
ResearchOpen Access16 May 2024
Nature Communications

Volume: 15, P: 1-11
Soliton and lump and travelling wave solutions of the (3 + 1) dimensional KPB like equation with analysis of chaotic behaviors

Yongyi Gu
Xiaoting Zhang
Najva Aminakbari
ResearchOpen Access06 Sept 2024
Scientific Reports

Volume: 14, P: 1-14
Human-induced water loss potentially threatens sustainable development of sandy regions in China

China’s sandy regions are experiencing a significant water loss due to increased farmland irrigation and revegetation, posing a potential 6.54% to 19.07% decrease in water supply capacity in the next 40 years, according to an integrated analysis of multiple datasets.

Runa A
Xinliang Pan
Tingwei Cui
ResearchOpen Access30 Jan 2025
Communications Earth & Environment

Volume: 6, P: 1-10
Synergistic optimization enhancing the precision and efficiency of cytosine base editors in poplar

A base editing study in poplar shows that synergistic optimization of a cytosine base editing system (hyPopCBE-V4) enhances C to T editing efficiency and precision, reduces byproducts, and yields herbicide-resistant germplasm, providing a tool for tree breeding.

Han Liu
Mengyu Zhang
Hai Lu
ResearchOpen Access10 Jun 2025
Communications Biology

Volume: 8, P: 1-15
PtomtAPX, a mitochondrial ascorbate peroxidase, plays an important role in maintaining the redox balance of Populus tomentosa Carr

Bin Yin
Jiaxue Zhang
Hai Lu
ResearchOpen Access20 Dec 2019
Scientific Reports

Volume: 9, P: 1-15
The LncRNA RP11-301G19.1/miR-582-5p/HMGB2 axis modulates the proliferation and apoptosis of multiple myeloma cancer cells via the PI3K/AKT signalling pathway

Faming Wang
Yao Luo
Liudi Yuan
Research11 Mar 2021
Cancer Gene Therapy

Volume: 29, P: 292-303
Treatment of relapsed or refractory classical Hodgkin lymphoma with the anti-PD-1, tislelizumab: results of a phase 2, single-arm, multicenter study

Yuqin Song
Quanli Gao
Jun Zhu
ResearchOpen Access13 Sept 2019
Leukemia

Volume: 34, P: 533-542

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Molecular basis of ligand binding and receptor activation at the human A₃ adenosine receptor

Morphology-dependent Electrochemical Enhancements of Porous Carbon as Sensitive Determination Platform for Ascorbic Acid, Dopamine and Uric Acid

Spontaneously established reverse electric field to enhance the performance of triboelectric nanogenerators via improving Coulombic efficiency

Soliton and lump and travelling wave solutions of the (3 + 1) dimensional KPB like equation with analysis of chaotic behaviors

Human-induced water loss potentially threatens sustainable development of sandy regions in China

Synergistic optimization enhancing the precision and efficiency of cytosine base editors in poplar

PtomtAPX, a mitochondrial ascorbate peroxidase, plays an important role in maintaining the redox balance of Populus tomentosa Carr

The LncRNA RP11-301G19.1/miR-582-5p/HMGB2 axis modulates the proliferation and apoptosis of multiple myeloma cancer cells via the PI3K/AKT signalling pathway

Treatment of relapsed or refractory classical Hodgkin lymphoma with the anti-PD-1, tislelizumab: results of a phase 2, single-arm, multicenter study

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