Nature Search

Bioinformatics analysis and identification of underlying biomarkers potentially linking allergic rhinitis and autophagy

Tao Zhou
Hua Cai
Jun Liu
ResearchOpen Access11 Nov 2024
Scientific Reports

Volume: 14, P: 1-10
Data-driven risk stratification and precision management of pulmonary nodules detected on chest computed tomography

Trained on a cohort of 45,064 cases and validated on data acquired from mobile computed tomography scanners deployed in rural China, a lung cancer screening deep learning model is shown to outperform existing lung cancer risk scores.

Chengdi Wang
Jun Shao
Weimin Li
ResearchOpen Access17 Sept 2024
Nature Medicine

Volume: 30, P: 3184-3195
A deep-learning-based framework for identifying and localizing multiple abnormalities and assessing cardiomegaly in chest X-ray

Accurate localization of abnormalities is crucial in the interpretation of chest X-rays. Here the authors present a deep learning framework for simultaneous localization of 14 thoracic abnormalities and calculation of cardiothoracic ratio, based on large X-ray dataset with bounding boxes created via a human-in-the-loop approach.

Weijie Fan
Yi Yang
Dong Zhang
ResearchOpen Access14 Feb 2024
Nature Communications

Volume: 15, P: 1-14
Nicking mechanism underlying the DNA phosphorothioate-sensing antiphage defense by SspE

SspABCD–SspE is a phosphorothioation-sensing bacterial defence system. Here, authors find that SspE exploits DNA phosphorothioation-binding preference to modulate its biochemical activities for the self/nonself discrimination and phage resistance.

Haiyan Gao
Xinqi Gong
Lianrong Wang
ResearchOpen Access09 Nov 2022
Nature Communications

Volume: 13, P: 1-12
The lncRNA H19 alleviates muscular dystrophy by stabilizing dystrophin

Zhang et al. report that the lncRNA H19 stabilizes dystrophin by competing with the ubiquitin E3 ligase TRIM63 for association with dystrophin, thereby alleviating muscular dystrophies.

Yaohua Zhang
Yajuan Li
Liuqing Yang
Research26 Oct 2020
Nature Cell Biology

Volume: 22, P: 1332-1345
Systematic identification of genes with a cancer-testis expression pattern in 19 cancer types

Genes normally expressed in the testis but aberrantly expressed in cancer are termed cancer testis antigens. In this study, the authors catalogue the expression of these genes in 19 different cancer types and correlate expression with some somatically mutated oncogenes.

Cheng Wang
Yayun Gu
Zhibin Hu
ResearchOpen Access27 Jan 2016
Nature Communications

Volume: 7, P: 1-12
Improved circulating tumor DNA identification for detection of esophageal squamous cell carcinoma by enzymatic methyl sequencing and hybrid neural network

Jiangfeng Shen
Yuqi Ren
Dong Jiang
ResearchOpen Access26 Sept 2025
Scientific Reports

Volume: 15, P: 1-15
Publisher Correction: Bioinformatics analysis and identification of underlying biomarkers potentially linking allergic rhinitis and autophagy

Tao Zhou
Hua Cai
Jun Liu
Amendments and CorrectionsOpen Access30 Jan 2025
Scientific Reports

Volume: 15, P: 1
Sex differences of fall-risk-increasing drugs in the middle-aged and elderly: a descriptive, cross-sectional study of FDA adverse event reporting system

Ying Zhao
Yuke Zhong
Weitao Lu
ResearchOpen Access29 Nov 2024
Scientific Reports

Volume: 14, P: 1-11
Historical patterns of rice farming explain modern-day language use in China and Japan more than modernization and urbanization

Sharath Chandra Guntuku
Thomas Talhelm
Lyle H. Ungar
ResearchOpen Access24 Dec 2024
Humanities and Social Sciences Communications

Volume: 11, P: 1-21
The lncRNA Snhg1-Vps13D vesicle trafficking system promotes memory CD8 T cell establishment via regulating the dual effects of IL-7 signaling

Yanyan Zhang
Baohua Li
Yuzhang Wu
ResearchOpen Access24 Mar 2021
Signal Transduction and Targeted Therapy

Volume: 6, P: 1-14
Author Correction: Sex differences of fall-risk-increasing drugs in the middle-aged and elderly: a descriptive, cross-sectional study of FDA adverse event reporting system

Ying Zhao
Yuke Zhong
Weitao Lu
Amendments and CorrectionsOpen Access05 Feb 2025
Scientific Reports

Volume: 15, P: 1
Alkaloids of Aconiti Lateralis Radix Praeparata inhibit growth of non-small cell lung cancer by regulating PI3K/Akt-mTOR signaling and glycolysis

Proteomics experiments, metabolomics analyses and network pharmacology combined with molecular biology results suggest that alkaloids of Aconiti Lateralis Radix Praeparata might treat NSCLC by regulating PI3K/Akt-mTOR signaling and glycolysis.

Wen Zhang
Shuhui Cai
Liuqing Di
ResearchOpen Access11 Sept 2024
Communications Biology

Volume: 7, P: 1-15
Genome-wide association analysis of 19,629 individuals identifies variants influencing regional brain volumes and refines their genetic co-architecture with cognitive and mental health traits

Genome-wide analyses in 19,629 individuals identify 365 independent variants associated with brain volumetric phenotypes. The study provides insight into the overlapping genetic architecture of brain volume measures and cognitive and mental health traits.

Bingxin Zhao
Tianyou Luo
Hongtu Zhu
Research01 Nov 2019
Nature Genetics

Volume: 51, P: 1637-1644
Bioglass promotes wound healing by inhibiting endothelial cell pyroptosis through regulation of the connexin 43/reactive oxygen species (ROS) signaling pathway

In this study, the authors demonstrated that bioactive glass promotes granulation formation, collagen deposition and angiogenesis to accelerate wound healing. Bioactive glass down-regulaties the connexin 43/reactive oxygen species signaling pathway to inhibit endothelial cell pyroptosis in vitro and in vivo.

Kailun Zhang
Bo Chai
Ke Xu
Research14 Sept 2021
Laboratory Investigation

Volume: 102, P: 90-101
Lamin-A interacting protein Hsp90 is required for DNA damage repair and chemoresistance of ovarian cancer cells

Yixuan Wang
Quan Chen
Xiaoying Wu
ResearchOpen Access12 Aug 2021
Cell Death & Disease

Volume: 12, P: 1-11
Bibliometric analysis and content analysis of digital entrepreneurship: utilizing the WoS and Scopus databases

Haijiao Liu
Jiahui Yu
Qing Liu
ReviewsOpen Access02 Apr 2025
Humanities and Social Sciences Communications

Volume: 12, P: 1-26
Chromosome-level genome assembly of the diploid oat species Avena longiglumis

Qing Liu
Gui Xiong
John Seymour Heslop-Harrison
ResearchOpen Access22 Apr 2024
Scientific Data

Volume: 11, P: 1-9

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Bioinformatics analysis and identification of underlying biomarkers potentially linking allergic rhinitis and autophagy

Data-driven risk stratification and precision management of pulmonary nodules detected on chest computed tomography

A deep-learning-based framework for identifying and localizing multiple abnormalities and assessing cardiomegaly in chest X-ray

Nicking mechanism underlying the DNA phosphorothioate-sensing antiphage defense by SspE

The lncRNA H19 alleviates muscular dystrophy by stabilizing dystrophin

Systematic identification of genes with a cancer-testis expression pattern in 19 cancer types

Improved circulating tumor DNA identification for detection of esophageal squamous cell carcinoma by enzymatic methyl sequencing and hybrid neural network

Publisher Correction: Bioinformatics analysis and identification of underlying biomarkers potentially linking allergic rhinitis and autophagy

Sex differences of fall-risk-increasing drugs in the middle-aged and elderly: a descriptive, cross-sectional study of FDA adverse event reporting system

Historical patterns of rice farming explain modern-day language use in China and Japan more than modernization and urbanization

The lncRNA Snhg1-Vps13D vesicle trafficking system promotes memory CD8 T cell establishment via regulating the dual effects of IL-7 signaling

Author Correction: Sex differences of fall-risk-increasing drugs in the middle-aged and elderly: a descriptive, cross-sectional study of FDA adverse event reporting system

Alkaloids of Aconiti Lateralis Radix Praeparata inhibit growth of non-small cell lung cancer by regulating PI3K/Akt-mTOR signaling and glycolysis

Genome-wide association analysis of 19,629 individuals identifies variants influencing regional brain volumes and refines their genetic co-architecture with cognitive and mental health traits

Bioglass promotes wound healing by inhibiting endothelial cell pyroptosis through regulation of the connexin 43/reactive oxygen species (ROS) signaling pathway

Lamin-A interacting protein Hsp90 is required for DNA damage repair and chemoresistance of ovarian cancer cells

Bibliometric analysis and content analysis of digital entrepreneurship: utilizing the WoS and Scopus databases

Chromosome-level genome assembly of the diploid oat species Avena longiglumis

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