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An RNA splicing system that excises DNA transposons from animal mRNAs

A new type of mRNA splicing mechanism discovered in Caenorhabditis elegans that detects and removes inverted repeats also occurs in human cells, thereby providing another strategy to protect against the negative effects of transposable elements.

Long-Wen Zhao
Christopher Nardone
Scott Kennedy
ResearchOpen Access10 Dec 2025
Nature

Volume: 649, P: 496-504
Mammalian nucleolar protein DCAF13 is essential for ovarian follicle maintenance and oocyte growth by mediating rRNA processing

Jue Zhang
Yin-Li Zhang
Heng-Yu Fan
Research03 Oct 2018
Cell Death & Differentiation

Volume: 26, P: 1251-1266
Maternal DCAF13 Regulates Chromatin Tightness to Contribute to Embryonic Development

Yang Liu
Long-Wen Zhao
Yan Jin
ResearchOpen Access18 Apr 2019
Scientific Reports

Volume: 9, P: 1-11