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Advanced filters: Author: Lore Wils Clear advanced filters

  • In this work, we combine LEDGINs with BRD4 modulator ZL0580 to achieve a functional HIV cure. This approach silences the virus by retargeting viral integration into silent chromatin and blocking enhancers, offering a powerful combination strategy to block-and-lock HIV.

    • Eline Pellaers
    • Julie Janssens
    • Zeger Debyser
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-22