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Showing 1–2 of 2 results
Advanced filters: Author: Lorenzo Brusini Clear advanced filters

  • In apicomplexan parasites, the conoid is a dynamic organelle of enigmatic function. This study establishes that the conoid movement is essential to control the flux of F-actin needed for myosin-dependent motility that powers invasion and egress.

    • Nicolas Dos Santos Pacheco
    • Lorenzo Brusini
    • Dominique Soldati-Favre
    Research
    Nature Microbiology
    Volume: 7, P: 1777-1790

  • The authors uncover one of the largest mitoribosomes, dedicated to translating only three proteins in lethal human eukaryotic pathogens of the Apicomplexa phylum. All members of mitochondrial DNA-containing Myzozoa, including Toxoplasma gondii, have commandeered three lineage-specific families of RNA-binding proteins to meticulously piece together over 40 mitochondrial rRNA fragments to build an operational mitoribosome.

    • Chaoyue Wang
    • Sari Kassem
    • Yonggen Jia
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-18