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Nature Communications (1)
npj Vaccines (1)

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CD4⁺ T cell protection against murine Salmonella infection is female-specific and estrogen-dependent

CD4⁺ T cells play critical roles in the immune response to intracellular bacterial infection. Here the authors suggest that CD4⁺ T cells can protect in a murine model of Salmonella infection but that the protection occurs in females and is oestrogen dependent.

Shaina J. D’Souza
Rebecca M. Horowitz
James B. McLachlan
ResearchOpen Access16 Apr 2026
Nature Communications

P: 1-14
Establishment of isotype-switched, antigen-specific B cells in multiple mucosal tissues using non-mucosal immunization

John T. Prior
Vanessa M. Limbert
James B. McLachlan
ResearchOpen Access31 May 2023
npj Vaccines

Volume: 8, P: 1-13

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CD4+ T cell protection against murine Salmonella infection is female-specific and estrogen-dependent

Establishment of isotype-switched, antigen-specific B cells in multiple mucosal tissues using non-mucosal immunization

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CD4⁺ T cell protection against murine Salmonella infection is female-specific and estrogen-dependent