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Author Correction: Mapping the temporal and spatial dynamics of the human endometrium in vivo and in vitro

Luz Garcia-Alonso
Louis-François Handfield
Roser Vento-Tormo
Amendments and CorrectionsOpen Access20 Dec 2022
Nature Genetics

Volume: 55, P: 165
Mapping the temporal and spatial dynamics of the human endometrium in vivo and in vitro

Single-cell and spatial transcriptomic profiling of the human endometrium highlights pathways governing the proliferative and secretory phases of the menstrual cycle. Analyses of endometrial organoids show that WNT and NOTCH signaling modulate differentiation into the secretory and ciliated epithelial lineages, respectively.

Luz Garcia-Alonso
Louis-François Handfield
Roser Vento-Tormo
ResearchOpen Access02 Dec 2021
Nature Genetics

Volume: 53, P: 1698-1711
COVID-19 progression and convalescence in common variable immunodeficiency patients show dysregulated adaptive immune responses and persistent type I interferon and inflammasome activation

Common variable immunodeficiency (CVID) is a prevalent primary immunodeficiency characterized by hypogammaglobulinemia, poor antibody responses, and enhanced susceptibility to infection. Here the authors examine CVID patients infected by SARS-CoV-2 and describe broad immune dysregulation, sustained type I IFN responses, altered B/T cell signaling, impaired NK cell differentiation, and persistent inflammasome activation.

Javier Rodríguez-Ubreva
Josep Calafell-Segura
Esteban Ballestar
ResearchOpen Access28 Nov 2024
Nature Communications

Volume: 15, P: 1-21
Spatial multiomics map of trophoblast development in early pregnancy

A multiomics single-cell atlas of the human maternal–fetal interface including the myometrium, combining spatial transcriptomics data with chromatin accessibility, provides a comprehensive analysis of cell states as placental cells infiltrate the uterus during early pregnancy.

Anna Arutyunyan
Kenny Roberts
Roser Vento-Tormo
ResearchOpen Access29 Mar 2023
Nature

Volume: 616, P: 143-151
Single-cell Atlas of common variable immunodeficiency shows germinal center-associated epigenetic dysregulation in B-cell responses

Common variable immunodeficiency (CVID) is the most prevalent primary immunodeficiency. Here the authors perform single-cell omics analyses in CVID-discordant monozygotic twins and show epigenetic and transcriptional alterations associated with activation in memory B cells.

Javier Rodríguez-Ubreva
Anna Arutyunyan
Esteban Ballestar
ResearchOpen Access01 Apr 2022
Nature Communications

Volume: 13, P: 1-18

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Author Correction: Mapping the temporal and spatial dynamics of the human endometrium in vivo and in vitro

Mapping the temporal and spatial dynamics of the human endometrium in vivo and in vitro

COVID-19 progression and convalescence in common variable immunodeficiency patients show dysregulated adaptive immune responses and persistent type I interferon and inflammasome activation

Spatial multiomics map of trophoblast development in early pregnancy

Single-cell Atlas of common variable immunodeficiency shows germinal center-associated epigenetic dysregulation in B-cell responses

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