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Showing 1–6 of 6 results
Advanced filters: Author: Louise M. Ince Clear advanced filters

  • Circadian rhythms have been shown to influence immune responses, but it is unclear whether this influences responses to vaccines. Here the authors show that dendritic cells migrate in a circadian rhythm meaning that interactions with T cells are altered leading to differential vaccine responses.

    • Louise Madeleine Ince
    • Coline Barnoud
    • Christoph Scheiermann
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-13

  • Rhythmic trafficking of dendritic cells to the tumour draining lymph node governs a circadian response of tumour-antigen-specific CD8+ T cells that is dependent on the circadian expression of the co-stimulatory molecule CD80.

    • Chen Wang
    • Coline Barnoud
    • Christoph Scheiermann
    ResearchOpen Access
    Nature
    Volume: 614, P: 136-143

  • Scheiermann and colleagues show that circadian clocks control the infiltration of dendritic cells into skin lymphatics in mice and humans, with a peak migration to the lymph nodes during the rest phase.

    • Stephan J. Holtkamp
    • Louise M. Ince
    • Christoph Scheiermann
    ResearchOpen Access
    Nature Immunology
    Volume: 22, P: 1375-1381

  • This Review considers the importance of the core circadian clock for regulating both innate and adaptive immune cell responses. The authors consider the implications for vaccination and other clinical strategies, highlighting the emerging field of chrono-immunotherapy.

    • Christoph Scheiermann
    • Julie Gibbs
    • Andrew Loudon
    Reviews
    Nature Reviews Immunology
    Volume: 18, P: 423-437