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Genome-wide association studies reveal novel loci associated with pyrethroid and organophosphate resistance in Anopheles gambiae and Anopheles coluzzii

Insecticide resistance in mosquitoes threatens the success of malaria control programmes. This study found that in different populations of a malaria mosquito species in West Africa, resistance is associated with different genes or different mutations in the same set of genes.

Eric R. Lucas
Sanjay C. Nagi
David Weetman
ResearchOpen Access16 Aug 2023
Nature Communications

Volume: 14, P: 1-11
Global population structure and genotyping framework for genomic surveillance of the major dysentery pathogen, Shigella sonnei

Whole genome sequencing is increasingly being adopted for Shigella sonnei outbreak investigation and surveillance, but there is no global classification standard. Here, the authors develop and validate a genomic framework implemented using open-source software, and demonstrate its application using surveillance data.

Jane Hawkey
Kalani Paranagama
Kathryn E. Holt
ResearchOpen Access11 May 2021
Nature Communications

Volume: 12, P: 1-12
A genomic surveillance framework and genotyping tool for Klebsiella pneumoniae and its related species complex

Klebsiella pneumoniae is a pathogen of increasing public health concern and antimicrobial resistance is becoming more prevalent. Here, the authors describe a K. pneumoniae genotyping tool, Kleborate, that can be used to identify lineages and detect antimicrobial resistance and virulence loci.

Margaret M. C. Lam
Ryan R. Wick
Kathryn E. Holt
ResearchOpen Access07 Jul 2021
Nature Communications

Volume: 12, P: 1-16
Cryptic population structure and insecticide resistance in Anopheles gambiae from the southern Democratic Republic of Congo

Tristan P. W. Dennis
Poppy Pescod
Francis Wat’senga Tezzo
ResearchOpen Access18 Sept 2024
Scientific Reports

Volume: 14, P: 1-12
Genomic insights of high-risk clones of ESBL-producing Escherichia coli isolated from community infections and commercial meat in southern Brazil

João Gabriel Material Soncini
Louise Cerdeira
Eliana Carolina Vespero
ResearchOpen Access07 Jun 2022
Scientific Reports

Volume: 12, P: 1-12
Genomic Features of High-Priority Salmonella enterica Serovars Circulating in the Food Production Chain, Brazil, 2000–2016

Daniel F. Monte
Nilton Lincopan
Mariza Landgraf
ResearchOpen Access30 Jul 2019
Scientific Reports

Volume: 9, P: 1-12

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Genome-wide association studies reveal novel loci associated with pyrethroid and organophosphate resistance in Anopheles gambiae and Anopheles coluzzii

Global population structure and genotyping framework for genomic surveillance of the major dysentery pathogen, Shigella sonnei

A genomic surveillance framework and genotyping tool for Klebsiella pneumoniae and its related species complex

Cryptic population structure and insecticide resistance in Anopheles gambiae from the southern Democratic Republic of Congo

Genomic insights of high-risk clones of ESBL-producing Escherichia coli isolated from community infections and commercial meat in southern Brazil

Genomic Features of High-Priority Salmonella enterica Serovars Circulating in the Food Production Chain, Brazil, 2000–2016

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Genome-wide association studies reveal novel loci associated with pyrethroid and organophosphate resistance in Anopheles gambiae and Anopheles coluzzii

Global population structure and genotyping framework for genomic surveillance of the major dysentery pathogen, Shigella sonnei

A genomic surveillance framework and genotyping tool for Klebsiella pneumoniae and its related species complex

Cryptic population structure and insecticide resistance in Anopheles gambiae from the southern Democratic Republic of Congo

Genomic insights of high-risk clones of ESBL-producing Escherichia coli isolated from community infections and commercial meat in southern Brazil

Genomic Features of High-Priority Salmonella enterica Serovars Circulating in the Food Production Chain, Brazil, 2000–2016

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