The transcription factor p63 is a master regulator of ectoderm development. Here the authors show that zebrafish p63 binds enhancers associated with neural genes to limit Sox3 binding and gene expression while also acting as a pioneer factor by promoting chromatin opening at epidermal gene enhancers.
- José M. Santos-Pereira
- Lourdes Gallardo-Fuentes
- Juan J. Tena
