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Acta Pharmacologica Sinica (4)
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Showing 1–8 of 8 results

Advanced filters: Author: Lu-lu Tian Clear advanced filters

Mid-gestational cell-type-specific transcriptomic signatures in the prefrontal and superior temporal cortex in Down syndrome

Here, Xiong et al investigate mid-gestational brain development from Down syndrome and control brain samples using single-nucleus RNA sequencing. They report cell-type- and region-specific transcriptional alterations associated with chr21 abnormalities.

Rui-Ze Niu
Lu-Lu Xue
Liu-Lin Xiong
ResearchOpen Access11 Dec 2025
Nature Communications

Volume: 16, P: 1-21
Combined anti-PD-1, HDAC inhibitor and anti-VEGF for MSS/pMMR colorectal cancer: a randomized phase 2 trial

In a randomized phase 2 trial comparing anti-PD-1 plus anti-VEGF plus an HDAC inhibitor versus anti-PD-1 plus an HDAC inhibitor in patients with MSS/pMMR colorectal cancer, the triplet combination led to significantly better 18-week progression-free survival.

Feng Wang
Ying Jin
Rui-Hua Xu
Research04 Mar 2024
Nature Medicine

Volume: 30, P: 1035-1043
Predicting the severity of mycoplasma pneumoniae pneumonia in pediatric and adult patients: a multicenter study

Li-Yong Zhuo
Jia-Wei Hao
Xiao-Ping Yin
ResearchOpen Access03 Oct 2024
Scientific Reports

Volume: 14, P: 1-10
Globally accurate potential energy surface for the ground-state HCS(X²A′) and its use in reaction dynamics

Yu-Zhi Song
Lu-Lu Zhang
Qing-Tian Meng
ResearchOpen Access29 Nov 2016
Scientific Reports

Volume: 6, P: 1-12
S-nitrosylation of Hsp90 promotes cardiac hypertrophy in mice through GSK3β signaling

Shuang Zhao
Tian-yu Song
Yong Ji
Research21 Dec 2021
Acta Pharmacologica Sinica

Volume: 43, P: 1979-1988
Activating BK channels ameliorates vascular smooth muscle calcification through Akt signaling

Feng-ling Ning
Jie Tao
Xue-mei Zhang
Research23 Jun 2021
Acta Pharmacologica Sinica

Volume: 43, P: 624-633
Targeted inhibition of calpain in mitochondria alleviates oxidative stress-induced myocardial injury

Dong Zheng
Ting Cao
Tian-qing Peng
Research23 Sept 2020
Acta Pharmacologica Sinica

Volume: 42, P: 909-920
Endothelial cell-specific anticoagulation reduces inflammation in a mouse model of acute lung injury

Jian Lou
Yue Hu
Hua-hao Shen
Research16 Nov 2018
Acta Pharmacologica Sinica

Volume: 40, P: 769-780