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Showing 1–4 of 4 results
Advanced filters: Author: Lucas Tindall Clear advanced filters

  • Inhibition of 5α-reductase has the potential to be extremely useful in the treatment of prostate cancer. However, the two largest trials to investigate the use of such drugs showed that, although the overall incidence of cancer was reduced, detected tumors were more aggressive than in patients treated with placebo. In this Review, the authors consider the mechanism of 5α-reductase inhibitors in the treatment of prostate cancer, and discuss the controversies surrounding their use in clinical practice.

    • Lucas P. Nacusi
    • Donald J. Tindall
    Reviews
    Nature Reviews Urology
    Volume: 8, P: 378-384

  • CDeep3M provides a user-friendly tool for deep-learning-based image segmentation via a cloud-based deep convolutional neural network. Demonstrations include challenging light, X-ray, and electron microscopy segmentation tasks.

    • Matthias G. Haberl
    • Christopher Churas
    • Mark H. Ellisman
    Research
    Nature Methods
    Volume: 15, P: 677-680

  • There are now nearly 1,000 completed bacterial and archaeal genomes available, but as most of them were chosen for sequencing on the basis of their physiology, the data are limited by a highly biased phylogenetic distribution. To explore the value added by choosing microbial genomes for sequencing on the basis of their evolutionary relationships, the genomes of 56 species of Bacteria and Archaea selected to maximize phylogenetic coverage are now sequenced and analysed.

    • Dongying Wu
    • Philip Hugenholtz
    • Jonathan A. Eisen
    ResearchOpen Access
    Nature
    Volume: 462, P: 1056-1060