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Showing 1–3 of 3 results
Advanced filters: Author: Lucy Golden-Mason Clear advanced filters
  • The authors of this Review provide an overview of the mechanisms by which HCV is currently understood and postulated to govern liver injury. These mechanisms include the regulation of apoptosis, steatosis, activation of hepatic stellate cells, and the cytotoxic lymphocyte response.

    • John A Mengshol
    • Lucy Golden-Mason
    • Hugo R Rosen
    Reviews
    Nature Clinical Practice Gastroenterology & Hepatology
    Volume: 4, P: 622-634
  • The function of autophagy and how this affects non-alcoholic fatty liver disease is not fully known. Here the authors show that in mice with a targeted disruption of the autophagy pathway in CD11c+ cells, development of NAFLD is accelerated involving IL-23 and blocking of IL-23 reduces disease.

    • Lauriane Galle-Treger
    • Doumet Georges Helou
    • Omid Akbari
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-16
  • Baumert, Maretti-Mira et al. integrate human epidemiological data and in vitro liver spheroid models to investigate PFHpA, an unregulated PFAS, in adolescent MASLD. Findings link PFHpA exposure to increased disease risk and identify key pathogenic mechanisms and potential therapeutic targets.

    • Brittney O. Baumert
    • Ana C. Maretti-Mira
    • Lida Chatzi
    ResearchOpen Access
    Communications Medicine
    Volume: 5, P: 1-15