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Showing 1–5 of 5 results
Advanced filters: Author: Ludovic Baron Clear advanced filters

  • Some cancer cells exhibit high loads of reactive iron in lysosomes, and this feature is exploited by using fentomycin-1, a newly developed small molecule, to induce ferroptosis.

    • Tatiana Cañeque
    • Leeroy Baron
    • Raphaël Rodriguez
    ResearchOpen Access
    Nature
    Volume: 642, P: 492-500

  • Depending on the cell cycle stage, cells can repair their genome via different pathways. Here the authors reveal mechanistic insights into repair of double strand breaks induced during G1 in an error-prone manner by Pol θ-dependent and PARP1-independent alt NHEJ during the SG2/M phases of the cell cycle

    • Wei Yu
    • Chloé Lescale
    • Ludovic Deriano
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-15

  • Genetic variants at multiple loci of chr5p15.33 have been associated with susceptibility to numerous cancers. Here the authors show that the association of one of these loci may be explained by a variant, rs36115365, influencing telomerase reverse transcriptase (TERT) expression via ZNF148.

    • Jun Fang
    • Jinping Jia
    • Laufey T. Amundadottir
    ResearchOpen Access
    Nature Communications
    Volume: 8, P: 1-17

  • An analysis of 101 ancient human genomes from the Bronze Age (3000–1000 bc) reveals large-scale population migrations in Eurasia consistent with the spread of Indo-European languages; individuals frequently had light skin pigmentation but were not lactose tolerant.

    • Morten E. Allentoft
    • Martin Sikora
    • Eske Willerslev
    Research
    Nature
    Volume: 522, P: 167-172