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Showing 1–11 of 11 results
Advanced filters: Author: Lukas Kuderna Clear advanced filters

  • This study generates genome assemblies for seven major haplogroups of the human Y chromosome at a unique resolution that overcomes the structurally complex regions within. These data enable the detection and profiling of epigenetic modifications among the considered haplogroups.

    • Paula Esteller-Cucala
    • Marc Palmada-Flores
    • Tomàs Marquès-Bonet
    ResearchOpen Access
    Communications Biology
    Volume: 6, P: 1-11

  • Due to various structural and sequence complexities, the human Y chromosome is challenging to sequence and characterize. Here, the authors develop a strategy to sequence native, unamplified flow sorted Y chromosomes with a nanopore sequencing platform, and report the first assembly of a human Y chromosome of African origin.

    • Lukas F. K. Kuderna
    • Esther Lizano
    • Tomas Marques-Bonet
    ResearchOpen Access
    Nature Communications
    Volume: 10, P: 1-8

  • Whole-genome alignment of 239 primate species reveals noncoding regulatory elements that are under selective constraint in primates but not in other placental mammals, that are enriched for variants that affect human gene expression and complex traits in diseases.

    • Lukas F. K. Kuderna
    • Jacob C. Ulirsch
    • Kyle Kai-How Farh
    ResearchOpen Access
    Nature
    Volume: 625, P: 735-742

  • Analysis of the genomes of 50 species of Lemuriformes shows high levels of genomic diversity, likely due to allele sharing, as well as population declines and inbreeding patterns resulting from ecological factors and human impacts in Madagascar.

    • Joseph D. Orkin
    • Lukas F. K. Kuderna
    • Tomas Marques Bonet
    Research
    Nature Ecology & Evolution
    Volume: 9, P: 42-56

  • Comparative analysis of Y chromosomes across 29 primate species reveals rapid evolution and shows different patterns of evolution among regions of the Y chromosome during primate diversification.

    • Yang Zhou
    • Xiaoyu Zhan
    • Guojie Zhang
    Research
    Nature Ecology & Evolution
    Volume: 7, P: 1114-1130

  • Asexual vertebrates are extremely rare. Here, the authors sequence the genome of the Amazon molly, an asexual fish, and find few signs of genetic degeneration but clonal polymorphism and high heterozygosity, which might explain the success of this species.

    • Wesley C. Warren
    • Raquel García-Pérez
    • Manfred Schartl
    ResearchOpen Access
    Nature Ecology & Evolution
    Volume: 2, P: 669-679

  • This Review explores the genetic basis of diversification and adaptation in non-human primates, including their responses to ecological and environmental changes.

    • Christian Roos
    • Lakshmi Seshadri
    • Jeffrey Rogers
    Reviews
    Nature Reviews Biodiversity
    Volume: 1, P: 353-370

  • A whole-genome alignment of 240 phylogenetically diverse species of eutherian mammal—including 131 previously uncharacterized species—from the Zoonomia Project provides data that support biological discovery, medical research and conservation.

    • Diane P. Genereux
    • Aitor Serres
    • Elinor K. Karlsson
    ResearchOpen Access
    Nature
    Volume: 587, P: 240-245