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Showing 1–7 of 7 results
Advanced filters: Author: Lynette Cegelski Clear advanced filters

  • Enterobacteriaceae modify cellulose with lipid-derived pEtN groups to promote biofilm cohesion. Here, using structural and biochemical analyses, the authors provide further insights into the molecular interactions of BcsA, BcsG, BcsB, and BcsC facilitating pEtN modification and secretion of cellulose.

    • Preeti Verma
    • Ruoya Ho
    • Jochen Zimmer
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-17

  • Fluorinated polyacetylene has typically proven to be inaccessible using traditional polymer synthesis, but there is much interest in its predicted properties. Now, a mechanochemical unzipping strategy has succeeded in the synthesis of a gold-coloured, semiconducting fluorinated polyacetylene with improved stability in air compared to polyacetylene.

    • Benjamin R. Boswell
    • Carl M. F. Mansson
    • Noah Z. Burns
    Research
    Nature Chemistry
    Volume: 13, P: 41-46

  • Filamentation has been implicated in bacterial survival of exposure to environmental stresses, but in this Opinion, Sheryl S. Justice and colleagues propose that the morphological plasticity of pathogenic bacteria is a direct and adaptive response to the sensing of environmental changes.

    • Sheryl S. Justice
    • David A. Hunstad
    • Scott J. Hultgren
    Reviews
    Nature Reviews Microbiology
    Volume: 6, P: 162-168

  • A new cryo-EM structure of the ~1 MDa Escherichia coli cellulose synthase macrocomplex reveals how cellulose biosynthesis and phosphoethanolamine (pEtN) modification are coupled to promote host-tissue adhesion.

    • Justin F. Acheson
    • Ruoya Ho
    • Jochen Zimmer
    Research
    Nature Structural & Molecular Biology
    Volume: 28, P: 310-318

  • Targeting bacterial virulence is an alternative approach to antimicrobial therapy. This Review considers recent efforts towards antivirulence-based drug discovery in the framework of marketable drugs, and discusses what challenges remain and the factors that are crucial to developing the antivirulence therapeutic approach.

    • Lynette Cegelski
    • Garland R. Marshall
    • Scott J. Hultgren
    Reviews
    Nature Reviews Microbiology
    Volume: 6, P: 17-27