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Leukemia (83)
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Showing 1–50 of 149 results

Advanced filters: Author: M Andreeff Clear advanced filters

Expression of Bcl-2-related genes in normal and AML progenitors: changes induced by chemotherapy and retinoic acid

M Andreeff
S Jiang
S Zhao
Research03 Nov 1999
Leukemia

Volume: 13, P: 1881-1892
Cellular pharmacology of mitoxantrone in p-glycoprotein-positive and -negative human myeloid leukemic cell lines

U Consoli
NT Van
M Andreeff
Research01 Dec 1997
Leukemia

Volume: 11, P: 2066-2074
Multilineage involvement of Philadelphia chromosome positive acute lymphoblastic leukemia

TM Schenk
A Keyhani
M Andreeff
Research29 May 1998
Leukemia

Volume: 12, P: 666-674
Effects of homoharringtonine alone and in combination with alpha interferon and cytosine arabinoside on ‘in vitro’ growth and induction of apoptosis in chronic myeloid leukemia and normal hematopoietic progenitors

G Visani
D Russo
S Tura
Research01 May 1997
Leukemia

Volume: 11, P: 624-628
Quantitation of minimal residual disease in acute myelogenous leukemia and myelodysplastic syndromes in complete remission by molecular cytogenetics of progenitor cells

H Engel
J Drach
M Andreeff
Research16 Apr 1999
Leukemia

Volume: 13, P: 568-577
BRD4-mediated repression of p53 is a target for combination therapy in AML

MDM2 and BET inhibitors have shown efficacy in AML treatment. Here, the authors show that the two compounds can synergize through both p53 protein stabilization and inhibition of BRD4-mediated repression of p53 target genes.

Anne-Louise Latif
Ashley Newcombe
Peter D. Adams
ResearchOpen Access11 Jan 2021
Nature Communications

Volume: 12, P: 1-16
Tumour-reprogrammed stromal BCAT1 fuels branched-chain ketoacid dependency in stromal-rich PDAC tumours

Zhu et al. show how cancer-associated fibroblasts (CAFs) regulate metabolism of branched-chain amino acids in pancreatic ductal adenocarcinomas. CAFs secrete and deliver branched-chain ketoacids to cancer cells by degrading proteins in the extracellular matrix that are internalized from the tumour microenvironment.

Ziwen Zhu
Abhinav Achreja
Deepak Nagrath
Research06 Jul 2020
Nature Metabolism

Volume: 2, P: 775-792
Granulocyte–macrophage colony-stimulating factor (GM-CSF) to increase efficacy of intensive sequential chemotherapy with etoposide, mitoxantrone and cytarabine (EMA) in previously treated acute myeloid leukemia: a multicenter randomized placebo-controlled trial (EMA91 Trial)

X Thomas
P Fenaux
E Archimbaud
Research09 Aug 1999
Leukemia

Volume: 13, P: 1214-1220
2-Chlorodeoxyadenosine therapy for idiopathic hypereosinophilic syndrome

NT Ueno
S Zhao
M Andreeff
Correspondence01 Aug 1997
Leukemia

Volume: 11, P: 1386-1390
A first-in-class, first-in-human, phase I trial of p28, a non-HDM2-mediated peptide inhibitor of p53 ubiquitination in patients with advanced solid tumours

M A Warso
J M Richards
T K Das Gupta
ResearchOpen Access28 Feb 2013
British Journal of Cancer

Volume: 108, P: 1061-1070
Correction: Long term results of venetoclax combined with FLAG-IDA induction and consolidation for newly diagnosed and relapsed or refractory acute myeloid leukemia

Courtney D. DiNardo
Wei-Ying Jen
Hagop M. Kantarjian
Amendments and Corrections10 Dec 2025
Leukemia

Volume: 40, P: 262
Inhibition of mitochondrial complex I reverses NOTCH1-driven metabolic reprogramming in T-cell acute lymphoblastic leukemia

Notch1 is frequently activated promoting T-cell acute lymphoblastic leukaemia (T-ALL). Here, the authors show that Notch1 induces oxidative phosphorylation dependency in T-ALL and synergism when inhibiting both mitochondrial complex I and glutaminolysis in preclinical murine and human xenograft models.

Natalia Baran
Alessia Lodi
Marina Konopleva
ResearchOpen Access19 May 2022
Nature Communications

Volume: 13, P: 1-20
FLAG-idarubicin and allogeneic stem cell transplantation for Ph-positive ALL beyond first remission

M Deane
M Koh
HG Prentice
Research17 Dec 1998
Bone Marrow Transplantation

Volume: 22, P: 1137-1143
Ras oncogene expression and DNA content in plasma cell dyscrasias: a flow cytofluorimetric study

M Danova
A Riccardi
G Mazzini
Research01 Nov 1990
British Journal of Cancer

Volume: 62, P: 781-785
The combined effects of IL-3 and PSC 833 on daunorubicin- and mitoxantrone cytotoxicity in two growth factor-dependent leukemic cell lines

J Asschert
E de Vries
E Vellenga
Research01 May 1997
Leukemia

Volume: 11, P: 680-686
Retraction Note: MEK inhibition enhances ABT-737-induced leukemia cell apoptosis via prevention of ERK-activated MCL-1 induction and modulation of MCL-1/BIM complex

M. Konopleva
M. Milella
M. Andreeff
Amendments and Corrections18 Jul 2024
Leukemia

Volume: 38, P: 2072
578 SURFACE MARKERS AND RNA CONTENT OF LEUKEMIC BLASTS IN ACUTE MYELOID LEUKEMIA OF CHILDHOOD AS A MEASURE OF STAGE OF MATURATION

J D Beck
M Haghbin
S Gupta
Research01 Apr 1978
Pediatric Research

Volume: 12, P: 460
Abrogation of nuclear receptors Nr4a3 andNr4a1 leads to development of acute myeloid leukemia

Shannon E Mullican
Shuo Zhang
Orla M Conneely
Research21 May 2007
Nature Medicine

Volume: 13, P: 730-735
A Phase I study of Milademetan (DS3032b) in combination with low dose cytarabine with or without venetoclax in acute myeloid leukemia: Clinical safety, efficacy, and correlative analysis

Jayastu Senapati
Muharrem Muftuoglu
Courtney D. DiNardo
ResearchOpen Access29 Jun 2023
Blood Cancer Journal

Volume: 13, P: 1-6
A phase two study of high dose blinatumomab in Richter’s syndrome

Philip A. Thompson
Xianli Jiang
William G. Wierda
Research08 Aug 2022
Leukemia

Volume: 36, P: 2228-2232
Modulation of docetaxel-induced apoptosis and cell cycle arrest by all- trans retinoic acid in prostate cancer cells

A Nehmé
P Varadarajan
R D Christen
ResearchOpen Access29 May 2001
British Journal of Cancer

Volume: 84, P: 1571-1576
Growth inhibition, cytokinesis failure and apoptosis of multidrug-resistant leukemia cells after treatment with P-glycoprotein inhibitory agents

G Lehne
P De Angelis
HE Rugstad
Research14 May 1999
Leukemia

Volume: 13, P: 768-778
New therapeutic strategies for the treatment of acute lymphoblastic leukaemia

New therapeutic strategies are needed to improve the cure rate and quality of life in patients with acute lymphoblastic leukaemia. In this Review, Pui and Jeha discuss emerging new treatments that could improve the clinical outcome for these patients.

Ching-Hon Pui
Sima Jeha
Reviews01 Feb 2007
Nature Reviews Drug Discovery

Volume: 6, P: 149-165
A phase II trial of ipilimumab, nivolumab, or ipilimumab and nivolumab with or without azacitidine in relapsed or refractory myelodysplastic neoplasms

Ian M. Bouligny
Guillermo Montalban-Bravo
Guillermo Garcia-Manero
Research17 Nov 2024
Leukemia

Volume: 39, P: 524-528
Identification and quantitation of tumour cells in cell suspensions: a comparison of cytology and flow cytometry

D J Perez
I W Taylor
M H Tattersall
Research01 Apr 1981
British Journal of Cancer

Volume: 43, P: 526-531
Cell kinetics in acute lymphoblastic leukaemia: Comparative analysis between adults and children

M Ffrench
JP Magaud
PA Bryon
Research01 Mar 1989
British Journal of Cancer

Volume: 59, P: 401-406
Early allogeneic transplantation for refractory or relapsed acute leukaemia following remission induction with FLAG

JL Byrne
E Dasgupta
NH Russell
Research14 May 1999
Leukemia

Volume: 13, P: 786-791
Induction of apoptosis by 2-chlorodeoxyadenosine in B cell chronic lymphocytic leukemia

R Castejón
JA Vargas
A Durántez
Research01 Aug 1997
Leukemia

Volume: 11, P: 1253-1257
Usefulness of detection of minimal residual disease by ‘hypermetaphase’ fluorescent in situ hybridization after allogeneic BMT for chronic myelogenous leukemia

D Seong
S Giralt
R Champlin
Research01 Mar 1997
Bone Marrow Transplantation

Volume: 19, P: 565-570
Extensive analysis of the retinoblastoma gene in adult T cell leukemia/lymphoma (ATL)

Y Hatta
Y Yamada
HP Koeffler
Research01 Jul 1997
Leukemia

Volume: 11, P: 984-989
Atypical response to all-trans retinoic acid in a der(5)t(5;17) acute promyelocytic leukemia

M-J Mozziconacci
C Liberatore
M Lafage-Pochitaloff
Research12 Jun 1999
Leukemia

Volume: 13, P: 862-868
Proliferative effects of several hematopoietic growth factors on acute myelogenous leukemia cells and correlation with treatment outcome

M Tsuzuki
K Ezaki
M Hirano
Research01 Dec 1997
Leukemia

Volume: 11, P: 2125-2130
Establishment of a retinoic acid-resistant human acute promyelocytic leukaemia (APL) model in human granulocyte-macrophage colony-stimulating factor (hGM-CSF) transgenic severe combined immunodeficiency (SCID) mice

Y Fukuchi
M Kizaki
Y Ikeda
Research01 Oct 1998
British Journal of Cancer

Volume: 78, P: 878-884
All-trans retinoic acid (ATRA) in patients with chronic myeloid leukemia in the chronic phase

D Russo
M Regazzi
AT Maiolo
Research08 May 1998
Leukemia

Volume: 12, P: 449-454
Cell-cycle distribution of urothelial tumour cells as measured by flow cytometry

L G Collste
Z Darzynkiewicz
M R Melamed
Research01 Dec 1979
British Journal of Cancer

Volume: 40, P: 872-877
Adjuvant treatment with cyclosporin A increases the toxicity of chemotherapy for remission induction in acute non-lymphocytic leukemia

D Damiani
M Michieli
M Baccarani
Research12 Aug 1998
Leukemia

Volume: 12, P: 1236-1240
Gfi-1 inhibits proliferation and colony formation of p210BCR/ABL-expressing cells via transcriptional repression of STAT 5 and Mcl-1

A R Soliera
S A Mariani
B Calabretta
Research30 Jan 2012
Leukemia

Volume: 26, P: 1555-1563
Analysis of the BCR-ABL protein in Philadelphia chromosome-positive adult acute lymphocytic leukemia

AW Bseiso
HM Kantarjian
R Arlinghaus
Research01 Sept 1997
Leukemia

Volume: 11, P: 1583-1587
Characterization of H⁺-ATPase-dependent activity of multidrug resistance-associated protein in homoharringtonine-resistant human leukemic K562 cells

Z Benderra
H Morjani
M Manfait
Research29 Oct 1998
Leukemia

Volume: 12, P: 1539-1544
Internal tandem duplication of FLT3 associated with leukocytosis in acute promyelocytic leukemia

H Kiyoi
T Naoe
R Ohno
Research01 Sept 1997
Leukemia

Volume: 11, P: 1447-1452
Internal tandem duplication of the FLT3 gene and clinical evaluation in childhood acute myeloid leukemia

T Iwai
S Yokota
T Fujimoto
Research27 Jan 1999
Leukemia

Volume: 13, P: 38-43
Immunohistochemical detection of DNA topoisomerase IIα, P-glycoprotein and multidrug resistance protein (MRP) in small-cell and non-small-cell lung cancer

J Kreisholt
M Sorensen
M Sehested
Research01 May 1998
British Journal of Cancer

Volume: 77, P: 1469-1473
Interphase cytogenetics reveals a high incidence of aneuploidy and intra-tumour heterogeneity in breast cancer

M Fiegl
C Tueni
J Drach
Research01 Jul 1995
British Journal of Cancer

Volume: 72, P: 51-55
A sustained increase in the endogenous level of cAMP reduces the retinoid concentration required for APL cell maturation to near physiological levels

N Quenech’Du
S Ruchaud
M Lanotte
Research22 Oct 1998
Leukemia

Volume: 12, P: 1829-1833
Flow cytometry in primary breast cancer: improving the prognostic value of the fraction of cells in the S-phase by optimal categorisation of cut-off levels

H Sigurdsson
B Baldetorp
J Ranstam
Research01 Nov 1990
British Journal of Cancer

Volume: 62, P: 786-790
Immunocytochemical detection of the multidrug resistance-associated protein and P-glycoprotein in acute myeloid leukemia: impact of antibodies, sample source and disease status

M Filipits
RW Suchomel
R Pirker
Research01 Jul 1997
Leukemia

Volume: 11, P: 1073-1077
Vitamin K2 and its derivatives induce apoptosis in leukemia cells and enhance the effect of all-trans retinoic acid

M Yaguchi
K Miyazawa
K Toyama
Research01 Jun 1997
Leukemia

Volume: 11, P: 779-787
Treatment of chronic myelogenous leukemia with nucleoside analogs deoxycoformycin and fludarabine

J Cortes
H Kantarjian
M Keating
Research01 Jun 1997
Leukemia

Volume: 11, P: 788-791
Use of the comet test in the evaluation of multidrug resistance of human cell lines

L Mattii
R Barale
M Petrini
Research08 May 1998
Leukemia

Volume: 12, P: 627-632
A high serum soluble Fas/APO-1 level is associated with a poor outcome of aggressive non-Hodgkin’s lymphoma

N Niitsu
K Sasaki
M Umeda
Research09 Sept 1999
Leukemia

Volume: 13, P: 1434-1440

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