Nature Search

Thrombospondin modulates melanoma-platelet interactions and melanoma tumour cell growth in vivo

H Boukerche
O Berthier-Vergnes
JL McGregor
Research01 Jul 1995
British Journal of Cancer

Volume: 72, P: 108-116
Thiorphan reprograms neurons to promote functional recovery after spinal cord injury

Thiorphan is identified as a new and effective drug treatment for spinal cord injury that can be adopted across nervous system disease states in the development of new therapies for human neurological disorders.

E. A. van Niekerk
C. Marques de Freria
M. H. Tuszynski
ResearchOpen Access29 Oct 2025
Nature

Volume: 648, P: 402-408
Circulating intercellular adhesion molecule-1 and E-selectin levels in gastric cancer

M Benekli
IH Güllü
D Firat
Research01 Jul 1998
British Journal of Cancer

Volume: 78, P: 267-271
Implantation of stimulated homologous macrophages results in partial recovery of paraplegic rats

O. Rapalino
O. Lazarov-Spiegler
M. Schwartz
Research01 Jul 1998
Nature Medicine

Volume: 4, P: 814-821
Peanut lectin binding properties of germinal centers of mouse lymphoid tissue

M. L. Rose
M. S. C. Birbeck
A. J. S. Davies
Research27 Mar 1980
Nature

Volume: 284, P: 364-366
Decreased binding of epidermal growth factor to BALB/c 3T3 mutant cells defective in glycoprotein synthesis

ROBERT M. PRATT
IRA PASTAN
Research02 Mar 1978
Nature

Volume: 272, P: 68-70
Neuroprotective effects of brain-derived neurotrophic factor in rodent and primate models of Alzheimer's disease

Mark Tuszynski and his colleagues show that brain-derived neurotrophic factor is neuroprotective and can improve cognition in rodent and primate models of Alzheimer's disease.

Alan H Nagahara
David A Merrill
Mark H Tuszynski
Research08 Feb 2009
Nature Medicine

Volume: 15, P: 331-337
Phase I trial of hES cell-derived dopaminergic neurons for Parkinson’s disease

Bilateral grafts of cryopreserved human embryonic stem cell-derived dopaminergic neuron progenitor cells into the putamen of patients with Parkinson’s disease in a phase I clinical trial showed safety, improvements in off-drug motor function and graft survival at 18 months after transplant.

V. Tabar
H. Sarva
C. Henchcliffe
ResearchOpen Access16 Apr 2025
Nature

Volume: 641, P: 978-983
Injured adult neurons regress to an embryonic transcriptional growth state

In mouse models of central nervous system injury, Htt is shown to be a key component of the regulatory program associated with reversion of the neuronal transcriptome to a less-mature state.

Gunnar H. D. Poplawski
Riki Kawaguchi
Mark H. Tuszynski
Research15 Apr 2020
Nature

Volume: 581, P: 77-82
Extensive spontaneous plasticity of corticospinal projections after primate spinal cord injury

Rosenzweig and colleagues show that incomplete cervical spinal cord injury in macaques triggers substantially greater sprouting of spared corticospinal axons below the lesion. The monkeys also recovered significant locomotor ability, correlating with the extent of anatomical 'repair'.

Ephron S Rosenzweig
Gregoire Courtine
Mark H Tuszynski
Research14 Nov 2010
Nature Neuroscience

Volume: 13, P: 1505-1510
Regeneration of lesioned CNS axons by neutralisation of neurite growth inhibitors: a short review

M E Schwab
Research01 Jun 1991
Spinal Cord

Volume: 29, P: 294-298
p75 neurotrophin receptor modulation in mild to moderate Alzheimer disease: a randomized, placebo-controlled phase 2a trial

A phase 2a trial of LM11A-31 in mild to moderate Alzheimer disease suggests that p75^NTR modulation is safe and attenuates measures of degeneration.

Hayley R. C. Shanks
Kewei Chen
Taylor W. Schmitz
ResearchOpen Access17 May 2024
Nature Medicine

Volume: 30, P: 1761-1770
Gossypol inhibition of mitosis, cyclin D1 and Rb protein in human mammary cancer cells and cyclin-D1 transfected human fibrosarcoma cells

M Ligueros
D Jeoung
M Sonenberg
Research01 Jul 1997
British Journal of Cancer

Volume: 76, P: 21-28
Chemotropic guidance facilitates axonal regeneration and synapse formation after spinal cord injury

The authors report a successfully targeted reinnervation of hindlimb sensory fibers projection into the CNS following spinal cord injury in rats. Cervical level 1 lesions followed by expression of the neurotrophin NT-3 in the appropriate brainstem target led to proper targeting of regenerating axons.

Laura Taylor Alto
Leif A Havton
Mark H Tuszynski
Research02 Aug 2009
Nature Neuroscience

Volume: 12, P: 1106-1113
Expression of the thrombospondin 1 fragment 167–569 in C6 glioma cells stimulates tumorigenicity despite reduced neovascularization

Florence de Fraipont
Michelle Keramidas
Jean-Jacques Feige
Research12 Apr 2004
Oncogene

Volume: 23, P: 3642-3649
Transglutaminase 2 overexpression induces depressive-like behavior and impaired TrkB signaling in mice

C D Pandya
N Hoda
A Pillai
Research13 Sept 2016
Molecular Psychiatry

Volume: 22, P: 745-753
Systemic long-term delivery of antibodies in immunocompetent animals using cellulose sulphate capsules containing antibody-producing cells

M Pelegrin
M Marin
M Piechaczyk
Research18 Jun 1998
Gene Therapy

Volume: 5, P: 828-834
Interrogation of gossypol therapy in glioblastoma implementing cell line and patient-derived tumour models

M A Jarzabek
V Amberger-Murphy
A T Byrne
ResearchOpen Access06 Nov 2014
British Journal of Cancer

Volume: 111, P: 2275-2286
Guidelines for the conduct of clinical trials for spinal cord injury (SCI) as developed by the ICCP panel: clinical trial outcome measures

J D Steeves
D Lammertse
A Privat
Reviews19 Dec 2006
Spinal Cord

Volume: 45, P: 206-221
Induction of thrombospondin-1 partially mediates the anti-angiogenic activity of dexrazoxane

S L Maloney
D C Sullivan
R Bicknell
ResearchOpen Access08 Sept 2009
British Journal of Cancer

Volume: 101, P: 957-966
Evolution of BCL-2/IgH hybrid gene RNA expression during treatment of T(14;18)-bearing follicular lymphomas

P Soubeyran
I Hostein
B Hœrni
ResearchOpen Access15 Oct 1999
British Journal of Cancer

Volume: 81, P: 860-869
TRE17/USP6 oncogene translocated in aneurysmal bone cyst induces matrix metalloproteinase production via activation of NF-κB

Y Ye
L M Pringle
M M Chou
Research26 Apr 2010
Oncogene

Volume: 29, P: 3619-3629
Angiogenesis in pterygium: study of microvessel density, vascular endothelial growth factor, and thrombospondin-1

M Aspiotis
E Tsanou
V Malamou-Mitsi
Research23 Jun 2006
Eye

Volume: 21, P: 1095-1101
Super-Mendelian inheritance mediated by CRISPR–Cas9 in the female mouse germline

In the early embryo, Cas9 expressed in the female germline induces double-stranded breaks that are corrected by homology-directed repair, biasing inheritance of a desired allele in mice.

Hannah A. Grunwald
Valentino M. Gantz
Kimberly L. Cooper
Research23 Jan 2019
Nature

Volume: 566, P: 105-109
Is a Positive Western Blot Proof of HIV Infection?

Eleni Papadopulos-Eleopulos
Valendar F. Turner
John M. Papadimitriou
Reviews01 Jun 1993
Bio/Technology

Volume: 11, P: 696-707
Thrombospondin 2 expression is correlated with inhibition of angiogenesis and metastasis of colon cancer

T Tokunaga
M Nakamura
Y Ueyama
ResearchOpen Access18 Dec 1998
British Journal of Cancer

Volume: 79, P: 354-359
Identification of novel vascular targets in lung cancer

X Zhuang
J M J Herbert
R Bicknell
ResearchOpen Access23 Dec 2014
British Journal of Cancer

Volume: 112, P: 485-494
Guidelines for the conduct of clinical trials for spinal cord injury as developed by the ICCP panel: clinical trial design

D Lammertse
M H Tuszynski
M Kalichman
Reviews19 Dec 2006
Spinal Cord

Volume: 45, P: 232-242
Gender-Specific Effect of Mthfr Genotype and Neonatal Vigabatrin Interaction on Synaptic Proteins in Mouse Cortex

Elinor Blumkin
Tamar Levav-Rabkin
Hava M Golan
Research13 Apr 2011
Neuropsychopharmacology

Volume: 36, P: 1714-1728
Response to Alternating Electric Fields of Tubulin Dimers and Microtubule Ensembles in Electrolytic Solutions

Iara B. Santelices
Douglas E. Friesen
Jack A. Tuszynski
ResearchOpen Access29 Aug 2017
Scientific Reports

Volume: 7, P: 1-11
Report of International Clinical Trials Workshop on Spinal Cord Injury February 20–21, 2004, Vancouver, Canada

J Steeves
J Fawcett
M Tuszynski
News10 Aug 2004
Spinal Cord

Volume: 42, P: 591-597
A dual promoter lentiviral vector for the in vivo evaluation of gene therapeutic approaches to axon regeneration after spinal cord injury

K Löw
A Blesch
M H Tuszynski
Research04 Mar 2010
Gene Therapy

Volume: 17, P: 577-591
Recommended guidelines for studies of human subjects with spinal cord injury

D K Anderson
M Beattie
B Zheng
Editorial12 Apr 2005
Spinal Cord

Volume: 43, P: 453-458
Guidelines for the conduct of clinical trials for spinal cord injury as developed by the ICCP panel: spontaneous recovery after spinal cord injury and statistical power needed for therapeutic clinical trials

J W Fawcett
A Curt
D Short
Reviews19 Dec 2006
Spinal Cord

Volume: 45, P: 190-205
Spontaneous plasticity in the injured spinal cord—implications for repair strategies

N Weidner
M H Tuszynski
News21 Jan 2002
Molecular Psychiatry

Volume: 7, P: 9-11
Guidelines for the conduct of clinical trials for spinal cord injury as developed by the ICCP Panel: clinical trial inclusion/exclusion criteria and ethics

M H Tuszynski
J D Steeves
A Privat
Reviews19 Dec 2006
Spinal Cord

Volume: 45, P: 222-231

Search

Thrombospondin modulates melanoma-platelet interactions and melanoma tumour cell growth in vivo

Thiorphan reprograms neurons to promote functional recovery after spinal cord injury

Circulating intercellular adhesion molecule-1 and E-selectin levels in gastric cancer

Implantation of stimulated homologous macrophages results in partial recovery of paraplegic rats

Peanut lectin binding properties of germinal centers of mouse lymphoid tissue

Decreased binding of epidermal growth factor to BALB/c 3T3 mutant cells defective in glycoprotein synthesis

Neuroprotective effects of brain-derived neurotrophic factor in rodent and primate models of Alzheimer's disease

Phase I trial of hES cell-derived dopaminergic neurons for Parkinson’s disease

Injured adult neurons regress to an embryonic transcriptional growth state

Extensive spontaneous plasticity of corticospinal projections after primate spinal cord injury

Regeneration of lesioned CNS axons by neutralisation of neurite growth inhibitors: a short review

p75 neurotrophin receptor modulation in mild to moderate Alzheimer disease: a randomized, placebo-controlled phase 2a trial

Gossypol inhibition of mitosis, cyclin D1 and Rb protein in human mammary cancer cells and cyclin-D1 transfected human fibrosarcoma cells

Chemotropic guidance facilitates axonal regeneration and synapse formation after spinal cord injury

Expression of the thrombospondin 1 fragment 167–569 in C6 glioma cells stimulates tumorigenicity despite reduced neovascularization

Transglutaminase 2 overexpression induces depressive-like behavior and impaired TrkB signaling in mice

Systemic long-term delivery of antibodies in immunocompetent animals using cellulose sulphate capsules containing antibody-producing cells

Interrogation of gossypol therapy in glioblastoma implementing cell line and patient-derived tumour models

Guidelines for the conduct of clinical trials for spinal cord injury (SCI) as developed by the ICCP panel: clinical trial outcome measures

Induction of thrombospondin-1 partially mediates the anti-angiogenic activity of dexrazoxane

Evolution of BCL-2/IgH hybrid gene RNA expression during treatment of T(14;18)-bearing follicular lymphomas

TRE17/USP6 oncogene translocated in aneurysmal bone cyst induces matrix metalloproteinase production via activation of NF-κB

Angiogenesis in pterygium: study of microvessel density, vascular endothelial growth factor, and thrombospondin-1

Super-Mendelian inheritance mediated by CRISPR–Cas9 in the female mouse germline

Is a Positive Western Blot Proof of HIV Infection?

Thrombospondin 2 expression is correlated with inhibition of angiogenesis and metastasis of colon cancer

Identification of novel vascular targets in lung cancer

Guidelines for the conduct of clinical trials for spinal cord injury as developed by the ICCP panel: clinical trial design

Gender-Specific Effect of Mthfr Genotype and Neonatal Vigabatrin Interaction on Synaptic Proteins in Mouse Cortex

Response to Alternating Electric Fields of Tubulin Dimers and Microtubule Ensembles in Electrolytic Solutions

Report of International Clinical Trials Workshop on Spinal Cord Injury February 20–21, 2004, Vancouver, Canada

A dual promoter lentiviral vector for the in vivo evaluation of gene therapeutic approaches to axon regeneration after spinal cord injury

Recommended guidelines for studies of human subjects with spinal cord injury

Guidelines for the conduct of clinical trials for spinal cord injury as developed by the ICCP panel: spontaneous recovery after spinal cord injury and statistical power needed for therapeutic clinical trials

Spontaneous plasticity in the injured spinal cord—implications for repair strategies

Guidelines for the conduct of clinical trials for spinal cord injury as developed by the ICCP Panel: clinical trial inclusion/exclusion criteria and ethics

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