In this review, Cottrill et al. discuss how the Cystic Fibrosis Transmembrane conductance Regulator (CFTR) interacts with the membrane into which it is inserted. They summarize recent insight into the ways lipids are imbalanced in CF epithelia and how the lipid environment affects CFTR.
- Kirsten A. Cottrill
- Carlos M. Farinha
- Nael A. McCarty