In this Article, the authors identify the mechanism of influenza virus transcription in viral ribonucleoproteins (vRNPs). This processive helical track mechanism is enabled by the extreme flexibility of the helical part of the vRNP, which allows the polymerase to move over the genome while bound to both RNA ends.
- Rocío Coloma
- Rocío Arranz
- Jaime Martín-Benito