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Erratum: The antibiotic kasugamycin mimics mRNA nucleotides to destabilize tRNA binding and inhibit canonical translation initiation

Frank Schluenzen
Chie Takemoto
Paola Fucini
Amendments and Corrections01 Nov 2006
Nature Structural & Molecular Biology

Volume: 13, P: 1033
The antibiotic kasugamycin mimics mRNA nucleotides to destabilize tRNA binding and inhibit canonical translation initiation

Frank Schluenzen
Chie Takemoto
Paola Fucini
Research24 Sept 2006
Nature Structural & Molecular Biology

Volume: 13, P: 871-878
Structural basis for the assembly and quinone transport mechanisms of the dimeric photosynthetic RC–LH1 supercomplex

Bacterial photosynthesis reflects the early stages of the evolution of photosynthesis. Here, the authors present a systematic study of the cryo-EM structures of the dimeric light harvesting–reaction center complexes and assembly variants from Rhodobacter sphaeroides, which delineated a hierarchical assembly pathway and quinone transport routes of the dimeric photosynthetic RC–LH1 core complex.

Peng Cao
Laura Bracun
Lu-Ning Liu
ResearchOpen Access13 Apr 2022
Nature Communications

Volume: 13, P: 1-12
Kastor and Polluks polypeptides encoded by a single gene locus cooperatively regulate VDAC and spermatogenesis

A number of testes-specific lncRNAs have been annotated but their roles remain largely unexplored. Here the authors identify two small peptides encoded by the lncRNA Gm9999, Kastor and Polluks, both of which are required for male fertility in mice.

Shintaro Mise
Akinobu Matsumoto
Keiichi I. Nakayama
ResearchOpen Access28 Feb 2022
Nature Communications

Volume: 13, P: 1-17
FGF9 monomer–dimer equilibrium regulates extracellular matrix affinity and tissue diffusion

Haruhiko Koseki and colleagues identify a gain-of-function mutation in Fgf9 in mice with elbow knee synostosis. They further show that this mutation prevents homodimerization of Fgf9, allowing increased diffusion of the altered protein through developing tissues.

Masayo Harada
Hirotaka Murakami
Haruhiko Koseki
Research15 Feb 2009
Nature Genetics

Volume: 41, P: 289-298
The methyltransferase METTL9 mediates pervasive 1-methylhistidine modification in mammalian proteomes

Only very few enzymes are known to catalyze protein histidine methylation. Here, the authors show that METTL9 is responsible for most 1-methylhistidine modifications in mouse and human proteomes, and characterize METTL9′s substrate specificity and potential cellular functions.

Erna Davydova
Tadahiro Shimazu
Pål Ø. Falnes
ResearchOpen Access09 Feb 2021
Nature Communications

Volume: 12, P: 1-14
Direct small-molecule inhibitors of KRAS: from structural insights to mechanism-based design

KRAS is one of the most frequently activated proteins in cancer, yet the development of RAS inhibitors has proven to be extremely challenging. Here, Shokat and Ostrem discuss the latest insights into RAS structure and dynamics, consider potential mechanisms of action for effective RAS inhibitors, and examine recent reports of direct RAS inhibitors.

Jonathan M. L. Ostrem
Kevan M. Shokat
Reviews29 Jul 2016
Nature Reviews Drug Discovery

Volume: 15, P: 771-785
Detection of lymph node metastasis of oesophageal cancer by RT-nested PCR for SCC antigen gene mRNA

M Kano
Y Shimada
M Imamura
ResearchOpen Access17 Dec 1999
British Journal of Cancer

Volume: 82, P: 429-435
ErbB kinases and NDF signaling in human prostate cancer cells

Adam W Grasso
Duanzhi Wen
Hsing-Jien Kung
Research27 Nov 1997
Oncogene

Volume: 15, P: 2705-2716
Ribozyme-mediated inactivation of mutant K-ras oncogene in a colon cancer cell line

T Tokunaga
T Tsuchida
M Nakamura
ResearchOpen Access22 Aug 2000
British Journal of Cancer

Volume: 83, P: 833-839
Identification and characterization of Asef2, a guanine–nucleotide exchange factor specific for Rac1 and Cdc42

Y Kawasaki
M Sagara
T Akiyama
Research18 Jun 2007
Oncogene

Volume: 26, P: 7620-7627
Clinicopathological significance of EZH2 mRNA expression in patients with hepatocellular carcinoma

T Sudo
T Utsunomiya
M Mori
ResearchOpen Access26 Apr 2005
British Journal of Cancer

Volume: 92, P: 1754-1758
Structural basis for the altered drug sensitivities of non-small cell lung cancer-associated mutants of human epidermal growth factor receptor

S Yoshikawa
M Kukimoto-Niino
S Yokoyama
Research20 Feb 2012
Oncogene

Volume: 32, P: 27-38
Transformation potency of ErbB heterodimer signaling is determined by B-Raf kinase

M Hatakeyama
N Yumoto
A Konagaya
Research05 Apr 2004
Oncogene

Volume: 23, P: 5023-5031
Effects of hormone replacement therapy on weight, abdominal fat distribution, and lipid levels in Japanese postmenopausal women

H Sumino
S Ichikawa
M Kurabayashi
Research14 Aug 2003
International Journal of Obesity

Volume: 27, P: 1044-1051

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Erratum: The antibiotic kasugamycin mimics mRNA nucleotides to destabilize tRNA binding and inhibit canonical translation initiation

The antibiotic kasugamycin mimics mRNA nucleotides to destabilize tRNA binding and inhibit canonical translation initiation

Structural basis for the assembly and quinone transport mechanisms of the dimeric photosynthetic RC–LH1 supercomplex

Kastor and Polluks polypeptides encoded by a single gene locus cooperatively regulate VDAC and spermatogenesis

FGF9 monomer–dimer equilibrium regulates extracellular matrix affinity and tissue diffusion

The methyltransferase METTL9 mediates pervasive 1-methylhistidine modification in mammalian proteomes

Direct small-molecule inhibitors of KRAS: from structural insights to mechanism-based design

Detection of lymph node metastasis of oesophageal cancer by RT-nested PCR for SCC antigen gene mRNA

ErbB kinases and NDF signaling in human prostate cancer cells

Ribozyme-mediated inactivation of mutant K-ras oncogene in a colon cancer cell line

Identification and characterization of Asef2, a guanine–nucleotide exchange factor specific for Rac1 and Cdc42

Clinicopathological significance of EZH2 mRNA expression in patients with hepatocellular carcinoma

Structural basis for the altered drug sensitivities of non-small cell lung cancer-associated mutants of human epidermal growth factor receptor

Transformation potency of ErbB heterodimer signaling is determined by B-Raf kinase

Effects of hormone replacement therapy on weight, abdominal fat distribution, and lipid levels in Japanese postmenopausal women

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