Nature Search

Single-shot Ad26 vaccine protects against SARS-CoV-2 in rhesus macaques

The protective efficacy of a single dose of adenovirus serotype 26 (Ad26) vector-based vaccine expressing the SARS-CoV-2 spike protein in non-human primates is demonstrated.

Noe B. Mercado
Roland Zahn
Dan H. Barouch
Research30 Jul 2020
Nature

Volume: 586, P: 583-588
Providing normative information increases intentions to accept a COVID-19 vaccine

The authors show that accurate information about descriptive norms can increase intentions to accept a vaccine for COVID-19. They show that these effects are largely consistent in the 23 included countries and are concentrated among people who were otherwise uncertain about accepting a vaccine.

Alex Moehring
Avinash Collis
Dean Eckles
ResearchOpen Access09 Jan 2023
Nature Communications

Volume: 14, P: 1-10
SIRT1 mediates obesity- and nutrient-dependent perturbation of pubertal timing by epigenetically controlling Kiss1 expression

The onset of mammalian puberty is sensitive to metabolic changes and nutritional status, but the mechanisms underlying this phenomenon are poorly understood. Here the authors show that the epigenetic regulator of transcription, SIRT1, mediates the effects of under and overnutrition on pubertal timing by controlling the expression of Kiss1 in hypothalamic neurons.

M. J. Vazquez
C. A. Toro
M. Tena-Sempere
ResearchOpen Access10 Oct 2018
Nature Communications

Volume: 9, P: 1-15
Photoinduced doping in heterostructures of graphene and boron nitride

Visible light can induce writing and erasing of charge doping in graphene/boron nitride heterostructures while maintaining high carrier mobility.

L. Ju
J. Velasco Jr
F. Wang
Research13 Apr 2014
Nature Nanotechnology

Volume: 9, P: 348-352
Escape from X inactivation of Smcx is preceded by silencing during mouse development

Patricia A. Lingenfelter
David A. Adler
Christine M. Disteche
Correspondence01 Mar 1998
Nature Genetics

Volume: 18, P: 212-213
Xyloglucan processing machinery in Xanthomonas pathogens and its role in the transcriptional activation of virulence factors

Xyloglucans are polysaccharides found in plant cell walls. Here, the authors describe the xyloglucan depolymerization machinery of phytopathogenic Xanthomonas bacteria, and show that sugars released by this system induce the expression of key virulence factors driving pathogenesis.

Plinio S. Vieira
Isabela M. Bonfim
Mario T. Murakami
ResearchOpen Access30 Jun 2021
Nature Communications

Volume: 12, P: 1-15
Magnetic configuration effects on the Wendelstein 7-X stellarator

Results from the first experimental campaign of the Wendelstein 7-X stellarator demonstrate that its magnetic-field design grants good control of parasitic plasma currents, leading to long energy confinement times.

A. Dinklage
C. D. Beidler
M. Zuin
Research21 May 2018
Nature Physics

Volume: 14, P: 855-860
Transcriptomic analysis links diverse hypothalamic cell types to fibroblast growth factor 1-induced sustained diabetes remission

In rodent models of type 2 diabetes, sustained remission of hyperglycemia can be induced by FGF1 action in the mediobasal hypothalamus. Here, the authors show that FGF1-injection is followed by marked changes in glial cell populations and that the sustained glycemic response is dependent on intact melanocortin signaling.

Marie A. Bentsen
Dylan M. Rausch
Tune H. Pers
ResearchOpen Access07 Sept 2020
Nature Communications

Volume: 11, P: 1-16
A conserved sorting-associated protein is mutant in chorea-acanthocytosis

Luca Rampoldi
Carol Dobson-Stone
Anthony P. Monaco
Research01 Jun 2001
Nature Genetics

Volume: 28, P: 119-120
Social memory deficit caused by dysregulation of the cerebellar vermis

Social memory integrates past experiences into social interactions by distinguishing familiar from novel conspecifics. In this study, the authors delineated a role of the cerebellum in organizing the neural matrix required for social memory.

Owen Y. Chao
Salil Saurav Pathak
Yi-Mei Yang
ResearchOpen Access26 Sept 2023
Nature Communications

Volume: 14, P: 1-19
Dental aesthetics as an expression of culture and ritual

E. Labajo González
B. Perea Pérez
M. Mar Robledo Acinas
Research23 Jan 2010
British Dental Journal

Volume: 208, P: 77-80
Resolving acceleration to very high energies along the jet of Centaurus A

Observations of the radio galaxy Centaurus A at teraelectronvolt energies resolve its large-scale jet and favour electron synchrotron processes as the source of its X-ray emission.

H. Abdalla
R. Adam
N. Żywucka
Research17 Jun 2020
Nature

Volume: 582, P: 356-359
Receptor subtype discrimination using extensive shape complementary designed interfaces

Chris Garcia, David Baker and colleagues use a computational approach to develop designed repeat protein binders (DRPBs), which function as human Frizzled (Fz) subtype-selective antagonists and enable identification of Fz subtypes active in different organs.

Luke T. Dang
Yi Miao
David Baker
Research13 May 2019
Nature Structural & Molecular Biology

Volume: 26, P: 407-414
Bleomycin hydrolase is associated with risk of sporadic Alzheimer's disease

Susana E. Montoya
Christopher E. Aston
Robert E. Ferrell
Correspondence01 Mar 1998
Nature Genetics

Volume: 18, P: 211-212
Sociodemographic factors associated with sexual dysfunction in Mexican women with spinal cord injury

M Moreno-Lozano
S Durán-Ortíz
J Quinzaños-Fresnedo
Research23 Feb 2016
Spinal Cord

Volume: 54, P: 746-749
Customised-sampling approach for pipe failure prediction in water distribution networks

Milad Latifi
Ramiz Beig Zali
Raziyeh Farmani
ResearchOpen Access06 Aug 2024
Scientific Reports

Volume: 14, P: 1-19
Interrelationship between differentiation and malignancy-associated properties in glioma

M C Frame
R I Freshney
R Shaw
Research01 Mar 1984
British Journal of Cancer

Volume: 49, P: 269-280
Author Correction: GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19

Erola Pairo-Castineira
Konrad Rawlik
J. Kenneth Baillie
Amendments and CorrectionsOpen Access11 Jul 2023
Nature

Volume: 619, P: E61
Avelumab maintenance in advanced urothelial carcinoma: biomarker analysis of the phase 3 JAVELIN Bladder 100 trial

Biomarker analysis of the phase 3 JAVELIN Bladder 100 trial leads to the development of a multi-parameter model comprising tumor and immune features that might identify patients with advanced urothelial cancer who will benefit from avelumab maintenance therapy.

Thomas Powles
Srikala S. Sridhar
Craig B. Davis
Research10 Dec 2021
Nature Medicine

Volume: 27, P: 2200-2211
Author Correction: Sex differences in fear memory consolidation via Tac2 signaling in mice

A. Florido
E. R. Velasco
R. Andero
Amendments and CorrectionsOpen Access18 Jul 2024
Nature Communications

Volume: 15, P: 1-2
Prelamin A causes progeria through cell-extrinsic mechanisms and prevents cancer invasion

Mutations in the metalloproteinase Zmpste24 preclude prelamin A processing and cause premature ageing. Here, de la Rosaet al.create mosaic Zmpste24 mice, revealing that cell-extrinsic effects are essential for accelerated ageing caused by prelamin A accumulation and that prelamin A reduces invasiveness of cancer cells.

Jorge de la Rosa
José M.P. Freije
Carlos López-Otín
ResearchOpen Access06 Aug 2013
Nature Communications

Volume: 4, P: 1-9
Squamate reptiles challenge paradigms of genomic repeat element evolution set by birds and mammals

Large-scale patterns of genomic repeat element evolution have been studied mainly in birds and mammals. Here, the authors analyze the genomes of over 60 squamate reptiles and show high variation in repeat elements compared to mammals and birds, and particularly high microsatellite seeding in snakes.

Giulia I. M. Pasquesi
Richard H. Adams
Todd A. Castoe
ResearchOpen Access17 Jul 2018
Nature Communications

Volume: 9, P: 1-11
Decrease in coccolithophore calcification and CO₂ since the middle Miocene

The impact of future and past carbonate chemistry changes on calcifying plankton is poorly understood. Here, the authors show that coccolithophore degree of calcification decreased significantly between 6 and 4 million years ago, in line with declining aqueous CO₂concentrations.

Clara T. Bolton
María T. Hernández-Sánchez
Heather M. Stoll
ResearchOpen Access14 Jan 2016
Nature Communications

Volume: 7, P: 1-13
Infectious complications after second allogeneic hematopoietic cell transplant in adult patients with hematological malignancies

Stephen M. Maurer
Kathleen A. Linder
Marisa H. Miceli
Research23 Sept 2022
Bone Marrow Transplantation

Volume: 57, P: 1820-1826
Imaging epilepsy with SISCOM

Marino M. Bianchin
Lauro Wichert-Ana
Américo C. Sakamoto
Correspondence06 Apr 2011
Nature Reviews Neurology

Volume: 7, P: 240
Quenched Magnon excitations by oxygen sublattice reconstruction in (SrCuO₂)_n/(SrTiO₃)₂ superlattices

M. Dantz
J. Pelliciari
T. Schmitt
ResearchOpen Access12 Sept 2016
Scientific Reports

Volume: 6, P: 1-7
Author Correction: Genotyping, sequencing and analysis of 140,000 adults from Mexico City

Andrey Ziyatdinov
Jason Torres
Roberto Tapia-Conyer
Amendments and CorrectionsOpen Access08 Feb 2024
Nature

Volume: 626, P: E18
Neurological recovery after traumatic spinal cord injury: prognostic value of magnetic resonance

Rubén Mora-Boga
Olalla Vázquez-Muíños
Antonio Montoto-Marqués
Research01 Feb 2022
Spinal Cord

Volume: 60, P: 533-539
Accelerated ageing in mice deficient in Zmpste24 protease is linked to p53 signalling activation

Ignacio Varela
Juan Cadiñanos
Carlos López-Otín
Research03 Aug 2005
Nature

Volume: 437, P: 564-568
The Somatic Mosaicism across Human Tissues Network

The Somatic Mosaicism across Human Tissues Network aims to create a reference catalogue of somatic mosaicism across different tissues and cells within individuals.

Tim H. H. Coorens
Ji Won Oh
Yuqing Wang
Reviews02 Jul 2025
Nature

Volume: 643, P: 47-59
Author Correction: HAWC observations of the acceleration of very-high-energy cosmic rays in the Cygnus Cocoon

A. U. Abeysekara
A. Albert
J. D. Álvarez
Amendments and Corrections06 Apr 2021
Nature Astronomy

Volume: 5, P: 724-725
Nitric oxide mediates aortic disease in mice deficient in the metalloprotease Adamts1 and in a mouse model of Marfan syndrome

Loss of the metalloproteinase Adamts1 leads to aortic pathology in mice due to increased NOS2-dependent NO production. Decreased Adamts1 expression, associated with increased NOS2 expression, occurs in Marfan syndrome (MFS) mice and in MFS patients, and NOS2 inhibition prevents and reverses aortic pathology in MFS mice.

Jorge Oller
Nerea Méndez-Barbero
Juan Miguel Redondo
Research09 Jan 2017
Nature Medicine

Volume: 23, P: 200-212
Early Pleistocene enamel proteome from Dmanisi resolves Stephanorhinus phylogeny

Palaeoproteomic analysis of dental enamel from an Early Pleistocene Stephanorhinus resolves the phylogeny of Eurasian Rhinocerotidae, by enabling the reconstruction of molecular evolution beyond the limits of ancient DNA preservation.

Enrico Cappellini
Frido Welker
Eske Willerslev
Research11 Sept 2019
Nature

Volume: 574, P: 103-107
Publisher Correction: Very-high-energy particle acceleration powered by the jets of the microquasar SS 433

A. U. Abeysekara
A. Albert
H. Zhou
Amendments and Corrections27 Nov 2018
Nature

Volume: 564, P: E38
TP53 minigene analysis of 161 sequence changes provides evidence for role of spatial constraint and regulatory elements on variant-induced splicing impact

Daffodil M. Canson
Inés Llinares-Burguet
Eladio A. Velasco-Sampedro
ResearchOpen Access08 May 2025
npj Genomic Medicine

Volume: 10, P: 1-11
Author Correction: Like-minded sources on Facebook are prevalent but not polarizing

Brendan Nyhan
Jaime Settle
Joshua A. Tucker
Amendments and CorrectionsOpen Access01 Nov 2023
Nature

Volume: 623, P: E9
Observation of the rare B_s⁰ →µ⁺µ⁻ decay from the combined analysis of CMS and LHCb data

Combined analysis of proton-proton collision data from the Large Hadron Collider at CERN by the CMS and LHCb collaborations leads to the observation of the extremely rare decay of the strange B meson into muons; the result is compatible with the standard model of particle physics, and does not show any signs of new physics, such as supersymmetry.

V. Khachatryan
A.M. Sirunyan
E. Pesen
ResearchOpen Access13 May 2015
Nature

Volume: 522, P: 68-72
Topologically guided tuning of Zr-MOF pore structures for highly selective separation of C6 alkane isomers

The separation of C6 alkane isomers is crucial to the petroleum refining industry, but the distillation methods in place are energy intensive. Here, the authors design a series of topologically-guided zirconium-based metal-organic frameworks with optimized pore structures for efficient C6 alkane isomer separations.

Hao Wang
Xinglong Dong
Jing Li
ResearchOpen Access01 May 2018
Nature Communications

Volume: 9, P: 1-11
Bricks and mortar of the epidermal barrier

Zoltan Nemes
Peter M Steinert
ResearchOpen Access01 Mar 1999
Experimental & Molecular Medicine

Volume: 31, P: 5-19
Native American ancestry significantly contributes to neuromyelitis optica susceptibility in the admixed Mexican population

Sandra Romero-Hidalgo
José Flores-Rivera
Teresa Corona
ResearchOpen Access13 Aug 2020
Scientific Reports

Volume: 10, P: 1-11
Microbial and physicochemical changes in green bell peppers treated with ultrasonic-assisted washing in combination with Thymus vulgaris essential oil nanocapsules

Saiede Akbari
Mohsen Radi
Sedigheh Amiri
ResearchOpen Access17 Jul 2024
Scientific Reports

Volume: 14, P: 1-16
Development of a CRISPR/Cas9-based therapy for Hutchinson–Gilford progeria syndrome

AAV-mediated CRISPR/Cas9 therapy extends life span and ameliorates disease-related phenotypes in a mouse model of Hutchinson–Gilford progeria syndrome.

Olaya Santiago-Fernández
Fernando G. Osorio
Carlos López-Otín
Research18 Feb 2019
Nature Medicine

Volume: 25, P: 423-426
Effect of Populus nigra spring and autumn leaves extract on Capsicum annuum infected with pepper mild mottle virus

H. A. Gharib
A. M. Mandour
ResearchOpen Access23 Dec 2022
Scientific Reports

Volume: 12, P: 1-11
Defective prelamin A processing and muscular and adipocyte alterations in Zmpste24 metalloproteinase–deficient mice

Alberto M. Pendás
Zhongjun Zhou
Carlos López-Otín
Research01 Apr 2002
Nature Genetics

Volume: 31, P: 94-99
HAWC observations of the acceleration of very-high-energy cosmic rays in the Cygnus Cocoon

Following HAWC observations of the Cygnus Cocoon, massive star-forming regions can now be considered to be sources of very-high-energy (TeV to PeV) Galactic cosmic rays.

A. U. Abeysekara
A. Albert
J. D. Álvarez
Research11 Mar 2021
Nature Astronomy

Volume: 5, P: 465-471
Late Miocene threshold response of marine algae to carbon dioxide limitation

New measurements of stable isotope vital effects in fossil coccoliths show a step increase in reliance of coccolithophore photosynthesis on active transport of dissolved bicarbonate in the late Miocene epoch, suggesting both a low threshold for adaptation of coccolithophores to carbon dioxide and a decrease in global carbon dioxide levels at that time.

Clara T. Bolton
Heather M. Stoll
Research28 Aug 2013
Nature

Volume: 500, P: 558-562
Very-high-energy particle acceleration powered by the jets of the microquasar SS 433

Observations of teraelectronvolt γ-rays accelerated by the jets of the miniature quasar SS 433 are reported.

A. U. Abeysekara
A. Albert
H. Zhou
Research03 Oct 2018
Nature

Volume: 562, P: 82-85
Loss of collagenase-2 confers increased skin tumor susceptibility to male mice

Milagros Balbín
Antonio Fueyo
Carlos López-Otín
Research28 Sept 2003
Nature Genetics

Volume: 35, P: 252-257
Combined treatment with statins and aminobisphosphonates extends longevity in a mouse model of human premature aging

Statins and aminobisphosphonates inhibit post-translational modifications and membrane accumulation of progerin, the protein that causes Hutchinson-Gilford progeria syndrome, pointing to a potential combination therapy for this disease.

Ignacio Varela
Sandrine Pereira
Carlos López-Otín
Research29 Jun 2008
Nature Medicine

Volume: 14, P: 767-772
Inhibition of a G9a/DNMT network triggers immune-mediated bladder cancer regression

Inhibition of histone and DNA methyltransferase activity enhances sensitivity to platinum-based and immunotherapy in a novel transgenic mouse model of metastatic bladder cancer.

Cristina Segovia
Edurne San José-Enériz
Jesús M. Paramio
Research03 Jul 2019
Nature Medicine

Volume: 25, P: 1073-1081

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