The structure of truncated Neurospora crassa mitochondrial tyrosyl-tRNA synthetase (CYT-18) with the intron ribozyme T wort orf142-I2 is solved. The interaction surface is different than that used by CYT-18 to bind tRNATyr when it is functioning as a tyrosyl-tRNA synthetase. The protein serves as a scaffold that extends the intron, facilitating its splicing function.
- Paul J. Paukstelis
- Jui-Hui Chen
- Barbara L. Golden
