The collective migration of epithelial cells arises from the interplay between intercellular forces and cellular signalling networks. It is now shown that the migration of an epithelium can be controlled by applying electric fields that bias the signalling networks, and that such galvanotactic control can prompt cell populations to make coordinated U-turns, undergo divergent or convergent migration, or move against an obstacle.
- Daniel J. Cohen
- W. James Nelson
- Michel M. Maharbiz