Nature Search

The 'last ribo-organism' was no breakthrough

NANCY MAIZELS
ALUN M. WEINER
Research23 Dec 1987
Nature

Volume: 330, P: 616
Biostratigraphy and assigning the paleosalinity by using Echinocorys and Planktonic foraminifera at Upper Maastrichtian, in Jorband section, Central Alborz, Iran

Masood Asgharian Rostami
Behnaz Balmaki
Esmail Kohansal
ResearchOpen Access02 Sept 2009
Nature Precedings

P: 1
Oxygen consumption of bumblebees in forward flight

C. P. Ellington
K. E. Machin
Timothy M. Casey
Research04 Oct 1990
Nature

Volume: 347, P: 472-473
The flight of the bumblebee

Jeremy M. V. Rayner
News & Views04 Oct 1990
Nature

Volume: 347, P: 422-423
A critical junction for RuvA

The structure of the RuvA tetramer suggests how Holliday junctions are maintained in a conformation that facilitates branch migration during recombination.

David M.J. Lilley
News & Views01 Dec 1996
Nature Structural Biology

Volume: 3, P: 984-986
Uncertainty in ancient phylogenies

Steven A. Benner
Thomas M. Jermann
Gaston H. Gonnet
Research14 Sept 1995
Nature

Volume: 377, P: 109-110
Design, biological activity and NMR-solution structure of a DNA analogue of yeast tRNA^Phe anticodon domain

M.M. Basti
J.W. Stuart
P.F. Agris
Research01 Jan 1996
Nature Structural Biology

Volume: 3, P: 38-44
Preliminary Experiments on the Chemistry and Pharmacology of Cannabis

E. W. GILL
W. D. M. PATON
R. G. PERTWEE
Research10 Oct 1970
Nature

Volume: 228, P: 134-136
Potential of ferroelectrics as radiation shields

M. T. LAGARE
N. UMAKANTHA
Research21 Apr 1988
Nature

Volume: 332, P: 689
Site-selective photocatalytic functionalization of peptides and proteins at selenocysteine

The modification of peptides and proteins for application in drug discovery and chemical biology is currently a rapidly growing field of research. Here, the authors report a photocatalytic diselenide contraction method for the dimerization and site-specific functionalisation of peptides and protein.

Luke J. Dowman
Sameer S. Kulkarni
Richard J. Payne
ResearchOpen Access12 Nov 2022
Nature Communications

Volume: 13, P: 1-12
Birth control for grey seals

R. G. Brown
W. C. Kimmins
W. D Bowen
Research04 Jan 1996
Nature

Volume: 379, P: 30-31
Effect of Vitamin A Deficiency on the Cerebro-spinal Fluid Pressure of the Chick

D. H. M. WOOLLAM
J. W. MILLEN
Research01 Jan 1955
Nature

Volume: 175, P: 41-42
Tracking bees with harmonic radar

J. R. Riley
A. D. Smith
G. M. Poppy
Research04 Jan 1996
Nature

Volume: 379, P: 29-30
Chelating Agents for Selective Growth of Bacteria

G. M. RICHARDSON
Research07 Jan 1961
Nature

Volume: 189, P: 78-79
Carotenogenesis in Haematococcus pluvialis

M. R. DROOP
Research01 Jan 1955
Nature

Volume: 175, P: 42
Recognition and sensing of low-epitope targets via ternary complexes with oligonucleotides and synthetic receptors

Recognition, differentiation and sensing of small molecules displaying only sparse functionalities using artificial receptors is extremely challenging. Now a method to selectively bind and recognise low-epitope targets has been developed. The approach uses the formation of ternary complexes between small-molecule targets, their non-specific organic (or organometallic) receptors, and aptamers.

Kyung-Ae Yang
Mihaela Barbu
Milan N. Stojanovic
Research28 Sept 2014
Nature Chemistry

Volume: 6, P: 1003-1008
Proteolytic fragment or new gene product?

ERIC P. HOFFMAN
LOUIS M. KUNKEL
ROBERT H. BROWN JR
Research01 Nov 1988
Nature

Volume: 336, P: 210
The creatine–phosphagen system is mechanoresponsive in pancreatic adenocarcinoma and fuels invasion and metastasis

Extracellular-matrix remodelling promotes tumour progression and metastasis. Papalazarou et al. demonstrate that mechanosensing affects pancreatic cancer cell migration, metabolism and ultimately metastatic potential by targeting the creatine–phosphagen ATP-recycling system.

Vassilis Papalazarou
Tong Zhang
Laura M. Machesky
Research20 Jan 2020
Nature Metabolism

Volume: 2, P: 62-80
Implications of the late Palaeozoic oxygen pulse for physiology and evolution

Jeffrey B. Graham
Nancy M. Aguilar
Carl Gans
Research11 May 1995
Nature

Volume: 375, P: 117-120
Landmark stability is a prerequisite for spatial but not discrimination learning

R. Biegler
R. G. M. Morris
Research18 Feb 1993
Nature

Volume: 361, P: 631-633
El Chichòn dust a persistent problem

FRANS J. M. RIETMEIJER
Research08 Mar 1990
Nature

Volume: 344, P: 114-115
The Vela glitch of Christmas 1988

P. M. McCulloch
P. A. Hamilton
E. A. King
Research30 Aug 1990
Nature

Volume: 346, P: 822-824
Stability Oracle: a structure-based graph-transformer framework for identifying stabilizing mutations

Engineering stabilized proteins is essential for industrial and pharmaceutical biotechnologies. Here, authors present Stability Oracle, a Graph-Transformer framework trained on protein masked microenvironments to predict protein thermodynamic stability, using less training data while achieving improved generalization.

Daniel J. Diaz
Chengyue Gong
Adam R. Klivans
ResearchOpen Access23 Jul 2024
Nature Communications

Volume: 15, P: 1-15
The DNA sequence and biological annotation of human chromosome 1

S. G. Gregory
K. F. Barlow
D. R. Bentley
Research18 May 2006
Nature

Volume: 441, P: 315-321
MRE11 liberates cGAS from nucleosome sequestration during tumorigenesis

The double-strand break sensor MRE11 is identified as a pivotal mediator of cGAS activation in response to multiple types of DNA damage.

Min-Guk Cho
Rashmi J. Kumar
Gaorav P. Gupta
ResearchOpen Access10 Jan 2024
Nature

Volume: 625, P: 585-592
Ribosome-mediated biosynthesis of pyridazinone oligomers in vitro

Ribosomes have evolved to polymerize L-α-amino acids into proteins comprising a peptide backbone. Here, a pyridazinone backbone is formed using ribosomes in vitro, producing a variety of sequence-defined alternating block-copolymers.

Joongoo Lee
Jaime N. Coronado
Michael C. Jewett
ResearchOpen Access24 Oct 2022
Nature Communications

Volume: 13, P: 1-9
Bacteriophages use an expanded genetic code on evolutionary paths to higher fitness

Translational reprogramming, which enables site-specific incorporation of non-natural amino acids into proteins, offers practical tools for studying protein function but also provides insights into the genetic code. Bacteriophages engineered with a 21-amino-acid genetic code make use of the additional noncanonical amino acid during in vitro evolution.

Michael J Hammerling
Jared W Ellefson
Jeffrey E Barrick
Research02 Feb 2014
Nature Chemical Biology

Volume: 10, P: 178-180
Emergence of methicillin resistance predates the clinical use of antibiotics

Methicillin-resistant strains of Staphylococcus aureus appeared in European hedgehogs in the pre-antibiotic era as a co-evolutionary adaptation to antibiotic-producing dermatophytes and have spread within the local hedgehog populations and between hedgehogs and secondary hosts.

Jesper Larsen
Claire L. Raisen
Anders R. Larsen
ResearchOpen Access05 Jan 2022
Nature

Volume: 602, P: 135-141
Biosensor and machine learning-aided engineering of an amaryllidaceae enzyme

Amaryllidaceae alkaloids, such as the Alzheimer’s medication galantamine, are currently extracted from low-yielding daffodils. Here, authors pair biosensor-assisted screening with machine learning-guided protein design to rapidly engineer an improved Amaryllidaceae enzyme in a microbial host.

Simon d’Oelsnitz
Daniel J. Diaz
Andrew D. Ellington
ResearchOpen Access07 Mar 2024
Nature Communications

Volume: 15, P: 1-14
Functional expression of opioid receptors and other human GPCRs in yeast engineered to produce human sterols

The yeast Saccharomyces cerevisiae is powerful for studying human G protein-coupled receptors as they can be coupled to its mating pathway. Here the authors engineer baker’s yeast to produce human sterols and show that vertebrate G protein coupled receptors are more sensitive in this membrane environment.

Björn D. M. Bean
Colleen J. Mulvihill
Vincent J. J. Martin
ResearchOpen Access24 May 2022
Nature Communications

Volume: 13, P: 1-15
The DNA sequence and analysis of human chromosome 6

A. J. Mungall
S. A. Palmer
S. Beck
Research23 Oct 2003
Nature

Volume: 425, P: 805-811
The DNA sequence and analysis of human chromosome 13

A. Dunham
L. H. Matthews
M. T. Ross
Research01 Apr 2004
Nature

Volume: 428, P: 522-528
The DNA sequence of human chromosome 22

I. Dunham
A. R. Hunt
K. P. O'Brien
Research02 Dec 1999
Nature

Volume: 402, P: 489-495
A novel RNA-binding motif in influenza A virus non-structural protein 1

The solution NMR structure of the RNA-binding domain from influenza virus non-structural protein 1 exhibits a novel dimeric six-helical protein fold. Distributions of basic residues and conserved salt bridges of dimeric NS1(1-73) suggest that the face containing antiparallel helices 2 and 2′ forms a novel arginine-rich nucleic acid binding motif.

Chen-ya Chien
Roberto Tejero
Gaetano T. Montelione
Correspondence01 Nov 1997
Nature Structural Biology

Volume: 4, P: 891-895
Erratum: The DNA sequence and biological annotation of human chromosome 1

S. G. Gregory
K. F. Barlow
D. R. Bentley
Amendments and Corrections26 Oct 2006
Nature

Volume: 443, P: 1013
Expanding the limits of the second genetic code with ribozymes

Flexizymes have been used to expand the scope of chemical substrates for ribosome-directed polymerization in vitro. Here the authors deduce design rules of Flexizyme-mediated tRNA acylation that more effectively predict the incorporation of new monomers into peptides.

Joongoo Lee
Kenneth E. Schwieter
Michael C. Jewett
ResearchOpen Access08 Nov 2019
Nature Communications

Volume: 10, P: 1-12
Crystal structure of the unique RNA-binding domain of the influenza virus NS1 protein

The nonstructural protein (NS1 protein) of the influenza A virus binds to several types of RNAs. X-ray crystallographic analysis of the RNA-binding domain reveals a unique topology for the monomer as well as a novel six-helix structure for the dimer.

Jinsong Liu
Patricia A. Lynch
Helen M. Berman
Correspondence01 Nov 1997
Nature Structural Biology

Volume: 4, P: 896-899
LAMP-Seq enables sensitive, multiplexed COVID-19 diagnostics using molecular barcoding

SARS-CoV-2 detection with LAMP-Seq combines isothermal amplification and barcoding with high-throughput sequencing.

Kerstin U. Ludwig
Ricarda M. Schmithausen
Jonathan L. Schmid-Burgk
Research29 Jun 2021
Nature Biotechnology

Volume: 39, P: 1556-1562
Engineering Escherichia coli to see light

These smart bacteria ‘photograph’ a light pattern as a high-definition chemical image.

Anselm Levskaya
Aaron A. Chevalier
Christopher A. Voigt
Research23 Nov 2005
Nature

Volume: 438, P: 441-442
Molecular-level analysis of the serum antibody repertoire in young adults before and after seasonal influenza vaccination

Antibodies that bind to both H1 and H3 influenza strains exist in the pre-vaccination serum repertoire of healthy adults; most vaccine-elicited clonotypes bind either H1 or H3 strains.

Jiwon Lee
Daniel R Boutz
George Georgiou
Research07 Nov 2016
Nature Medicine

Volume: 22, P: 1456-1464
Correction: Room temperature CRISPR diagnostics for low-resource settings

Eric A. Nalefski
Selma Sinan
Damian Madan
Amendments and CorrectionsOpen Access04 Nov 2025
Scientific Reports

Volume: 15, P: 1
PSMA-targeting TGFβ-insensitive armored CAR T cells in metastatic castration-resistant prostate cancer: a phase 1 trial

CAR T cells targeting PSMA and engineered to be resistant to immunosuppressive TGFβ signaling exhibit dose-dependent toxicity and expansion following infusion, with some transient antitumor activity, in patients with metastatic castration-resistant prostate cancer

Vivek Narayan
Julie S. Barber-Rotenberg
Naomi B. Haas
Research21 Mar 2022
Nature Medicine

Volume: 28, P: 724-734
SLC25A51 is a mammalian mitochondrial NAD⁺ transporter

SLC25A51 is identified as a transporter of intact NAD⁺ into mammalian mitochondria and is required to maintain the mitochondrial NAD⁺ pool and respiratory function.

Timothy S. Luongo
Jared M. Eller
Joseph A. Baur
Research09 Sept 2020
Nature

Volume: 588, P: 174-179
Capturing the cloud of diversity reveals complexity and heterogeneity of MRSA carriage, infection and transmission

Populations of bacterial pathogens can be diverse within colonized individuals. Here, the authors sequence the genomes of methicillin-resistant Staphylococcus aureusisolated from staff and animal patients at a veterinary hospital and show considerable within-host diversity that can rise and fall over time.

Gavin K. Paterson
Ewan M. Harrison
Mark A. Holmes
ResearchOpen Access27 Mar 2015
Nature Communications

Volume: 6, P: 1-10
Denitrifying community in coastal sediments performs aerobic and anaerobic respiration simultaneously

Hannah K Marchant
Soeren Ahmerkamp
Marcel M M Kuypers
Research02 May 2017
The ISME Journal

Volume: 11, P: 1799-1812
Emergence and clonal spread of colistin resistance due to multiple mutational mechanisms in carbapenemase-producing Klebsiella pneumoniae in London

Jonathan A. Otter
Michel Doumith
Alison Holmes
ResearchOpen Access05 Oct 2017
Scientific Reports

Volume: 7, P: 1-8
The DNA sequence and comparative analysis of human chromosome 20

P. Deloukas
L. H. Matthews
J. Rogers
Research20 Dec 2001
Nature

Volume: 414, P: 865-871
Highly parallel single-molecule identification of proteins in zeptomole-scale mixtures

Single-protein molecules are identified in parallel through fluorescence monitoring of Edman degradation.

Jagannath Swaminathan
Alexander A Boulgakov
Edward M Marcotte
Research22 Oct 2018
Nature Biotechnology

Volume: 36, P: 1076-1082
Correction: Corrigendum: The zebrafish reference genome sequence and its relationship to the human genome

Kerstin Howe
Matthew D. Clark
Derek L. Stemple
Amendments and Corrections11 Dec 2013
Nature

Volume: 505, P: 248
TALEN and CRISPR/Cas9-mediated genome editing in the early-branching metazoan Nematostella vectensis

Genome editing has yet to be performed in non-bilaterian phyla. Here, Ikmi et al. develop techniques to use both TALEN and CRISPR/Cas9 in the sea anemone, Nematostella vectensis, and further leverage a locus expressing an endogenous fluorescent protein as a landing site for homologous recombination-mediated transgenesis.

Aissam Ikmi
Sean A. McKinney
Matthew C. Gibson
Research24 Nov 2014
Nature Communications

Volume: 5, P: 1-8

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