Nature Search

Regional source apportionment of trace metals in fine particulate matter using an observation-constrained hybrid model

Kezheng Liao
Jie Zhang
Jian Zhen Yu

ResearchOpen Access09 Jun 2023

npj Climate and Atmospheric Science

Volume: 6, P: 1-11

DRAG in situ barcoding reveals an increased number of HSPCs contributing to myelopoiesis with age

Using in situ single cell lineage tracing technology DRAG, we show that, unlike emergency myelopoiesis post-transplantation, aged HSPCs do not functionally decline in the number of myeloid cells that they produce.

Jos Urbanus
Jason Cosgrove
Leïla Perié

ResearchOpen Access17 Apr 2023

Nature Communications

Volume: 14, P: 1-14

Cox proportional hazards regression in small studies of predictive biomarkers

K. Jóźwiak
V. H. Nguyen
M. Hauptmann

ResearchOpen Access20 Jun 2024

Scientific Reports

Volume: 14, P: 1-11

Parameter influence on the mechanical properties of FFF printed PLA/copper for EV lightweight dashboard analysis

Yaw Chong Tak
A. Kottasamy
Johnny Koh Siaw Paw

ResearchOpen Access23 Oct 2025

Scientific Reports

Volume: 15, P: 1-25

LARP7-like protein Pof8 regulates telomerase assembly and poly(A)+TERRA expression in fission yeast

A functional telomerase complex requires that the catalytic TERT subunit be assembled with the template RNA TER1. Here the authors show that Pof8, a possible LARP7 family protein, is required for assembly of the telomerase complex, and repression of lncRNA transcripts at telomeres in S. pombe.

Amanda K. Mennie
Bettina A. Moser
Toru M. Nakamura

ResearchOpen Access08 Feb 2018

Nature Communications

Volume: 9, P: 1-12

Combinatorial immunotherapies overcome MYC-driven immune evasion in triple negative breast cancer

The oncoprotein c-Myc is often overexpressed in triple negative breast cancer and has a role in tumor progression and resistance to therapy. Here the authors show that elevated MYC expression is correlated with low immune infiltration, diminished MHC-I pathway expression and that CpG/aOX40 treatment could overcome resistance to PD-L1 blockade in MYC-high breast tumors.

Joyce V. Lee
Filomena Housley
Andrei Goga

ResearchOpen Access27 Jun 2022

Nature Communications

Volume: 13, P: 1-12

In Vivo Study of Phytanic Acid α-Oxidation in Classic Refsum's Disease and Chondrodysplasia Punctata

Herman J Ten Brink
Danielle S M Schor
Cornelis Jakobs

Research01 Nov 1992

Pediatric Research

Volume: 32, P: 566-570

A systematic benchmark of Nanopore long-read RNA sequencing for transcript-level analysis in human cell lines

This analysis provides a collection of sequencing datasets generated from long-read and short-read RNA sequencing, serving as a valuable resource for transcriptome profiling.

Ying Chen
Nadia M. Davidson
Jonathan Göke

ResearchOpen Access13 Mar 2025

Nature Methods

Volume: 22, P: 801-812

Regional and institutional trends in assessment for academic promotion

Analysis of policies for promotion criteria to full professor from academic institutions and government agencies worldwide reveals considerable variation in assessment practices, particularly between the Global North and South.

B. H. Lim
C. D’Ippoliti
Y. Flores Bueso

ResearchOpen Access22 Jan 2025

Nature

Volume: 638, P: 459-468

Spinal cord injury during windsurfing

M K Patel
R J Abbott
W J Marshall

Research01 Jun 1986

Spinal Cord

Volume: 24, P: 191-193

[¹¹C]Martinostat PET analysis reveals reduced HDAC I availability in Alzheimer’s disease

The link between amyloid and tau proteins with Alzheimer’s disease progression remains unclear. Here, the authors propose HDACs I downregulation as an element linking the deleterious effects of brain proteinopathies with disease progression.

Tharick A. Pascoal
Mira Chamoun
Pedro Rosa-Neto

ResearchOpen Access19 Jul 2022

Nature Communications

Volume: 13, P: 1-11

Childhood amyotrophic lateral sclerosis caused by excess sphingolipid synthesis

Clinical and genetic evaluation of individuals with childhood-onset amyotrophic lateral sclerosis identifies a new monogenic cause for early-onset ALS and proposes a specific metabolic mechanism leading to motor neuron disease via sphingolipid excess.

Payam Mohassel
Sandra Donkervoort
Carsten G. Bönnemann

Research31 May 2021

Nature Medicine

Volume: 27, P: 1197-1204

Phase II study of bi-weekly administration of paclitaxel and cisplatin in patients with advanced oesophageal cancer

M B Polee
F A L M Eskens
A van der Gaast

ResearchOpen Access26 Feb 2002

British Journal of Cancer

Volume: 86, P: 669-673

Selenium intakes in 18–64-y-old Irish adults

J Murphy
EM Hannon
KD Cashman

Research08 May 2002

European Journal of Clinical Nutrition

Volume: 56, P: 402-408

An explainable longitudinal multi-modal fusion model for predicting neoadjuvant therapy response in women with breast cancer

Deep learning for medical image analysis is a promising new avenue to predict treatment response, however the clinical application of these methods has been so far limited. Here, the authors propose a model to predict chemotherapy response in breast cancer in real world clinical settings.

Yuan Gao
Sofia Ventura-Diaz
Ritse Mann

ResearchOpen Access07 Nov 2024

Nature Communications

Volume: 15, P: 1-17

Aberrant transcripts of the FHIT gene are expressed in normal and leukaemic haemopoietic cells

M Carapeti
RC Aguiar
NCP Cross

Research01 Sept 1998

British Journal of Cancer

Volume: 78, P: 601-605

Mutation-specific reporter for optimization and enrichment of prime editing

While prime editing is a promising technique, some genomic sites remain difficult to edit. Here the authors present fluoPEER, fluorescent prime editing and enrichment reporter, to rank the efficiency of pegRNAs and prime editor variants.

I. F. Schene
I. P. Joore
S. A. Fuchs

ResearchOpen Access01 Mar 2022

Nature Communications

Volume: 13, P: 1-10

Co-infection with SARS-CoV-2 Omicron and Delta variants revealed by genomic surveillance

Here, using genomic approaches, Rockett et al. identify Omicron and Delta SARS-CoV-2 co-infections in two adults, highlighting the usefulness of genomic surveillance for the timely recognition of co-infections in situations when different variants of the virus are circulating in the community.

Rebecca J. Rockett
Jenny Draper
Vitali Sintchenko

ResearchOpen Access18 May 2022

Nature Communications

Volume: 13, P: 1-7

Chemotherapy with cisplatin and paclitaxel in patients with locally advanced, recurrent or metastatic oesophageal cancer

S Petrasch
A Welt
W Schmiegel

Research01 Aug 1998

British Journal of Cancer

Volume: 78, P: 511-514

Presentation and characterisation of the ALBA micro8 system for targeted hyperthermia in small animal research

J. A. Groen
R. Zweije
H. P. Kok

ResearchOpen Access29 Oct 2025

Scientific Reports

Volume: 15, P: 1-13

Evaluation of the US COVID-19 Scenario Modeling Hub for informing pandemic response under uncertainty

The US COVID-19 Scenario Modeling Hub produced medium to long term projections based on different epidemic scenarios. In this study, the authors evaluate 14 rounds of projections by comparing them to the epidemic trajectories that occurred, and discuss lessons learned for future similar projects.

Emily Howerton
Lucie Contamin
Justin Lessler

ResearchOpen Access20 Nov 2023

Nature Communications

Volume: 14, P: 1-15

Population dynamics of an Escherichia coli ST131 lineage during recurrent urinary tract infection

Recurrent urinary tract infections occur in ~ 25% of women. Here, Beatson and colleagues use whole genome sequencing to track the dynamics of an E. coli ST131 clone in a single patient over a 5-year period. This study provides unique insights into pathogen evolution during recurrent urinary infection.

Brian M. Forde
Leah W. Roberts
Scott A. Beatson

ResearchOpen Access13 Aug 2019

Nature Communications

Volume: 10, P: 1-10

Isolation of MERS-related coronavirus from lesser bamboo bats that uses DPP4 and infects human-DPP4-transgenic mice

Several human coronaviruses (CoV) have been proposed to emerge from bats but evidence of direct bat-to-human transmission is slim. In this work, the authors isolate a MERS-related CoV strain directly from bats and show that it infects target cells in vitro and engineered mice through the human DDP4 receptor.

Susanna K. P. Lau
Rachel Y. Y. Fan
Patrick C. Y. Woo

ResearchOpen Access11 Jan 2021

Nature Communications

Volume: 12, P: 1-10

The selection process of licensing a DNA mismatch for repair

Cryo–EM reconstructions and atomic models reveal the mechanism of MutS–MutL DNA mismatch recognition and repair initiation.

Rafael Fernandez-Leiro
Doreth Bhairosing-Kok
Meindert H. Lamers

Research05 Apr 2021

Nature Structural & Molecular Biology

Volume: 28, P: 373-381

LCOR mediates interferon-independent tumor immunogenicity and responsiveness to immune-checkpoint blockade in triple-negative breast cancer

Celià-Terrassa and colleagues identify LCOR-low cancer stem cells driving tumor immunity and propose LCOR induction with mRNA therapy as an enhancer of immunotherapy response.

Iván Pérez-Núñez
Catalina Rozalén
Toni Celià-Terrassa

Research17 Mar 2022

Nature Cancer

Volume: 3, P: 355-370

[6S]5-methyltetrahydrofolate or folic acid supplementation and absorption and initial elimination of folate in young and middle-aged adults

K de Meer
Y M Smulders
C Jakobs

Research07 Sept 2005

European Journal of Clinical Nutrition

Volume: 59, P: 1409-1416

Transit amplifying cells coordinate mouse incisor mesenchymal stem cell activation

Mouse incisor growth depends upon mesenchymal stromal cells (MSCs) and transit amplifying cells (TACs). Here the authors describe a distinct population of MSCs that is maintained by TACs through Dlk1 ligand and that contribute to MTACs and mesenchymal lineages including dental pulp and odontoblasts.

Jemma Victoria Walker
Heng Zhuang
Bing Hu

ResearchOpen Access09 Aug 2019

Nature Communications

Volume: 10, P: 1-18

A strong no-go theorem on the Wigner’s friend paradox

For a scenario of two separated but entangled observers, inequalities are derived from three fundamental assumptions. An experiment shows that these inequalities can be violated if quantum evolution is controllable on the scale of an observer.

Kok-Wei Bong
Aníbal Utreras-Alarcón
Howard M. Wiseman

Research17 Aug 2020

Nature Physics

Volume: 16, P: 1199-1205

Time-compressed preplay of anticipated events in human primary visual cortex

Perception is guided by anticipating future events, but it is not clear how this is computed neurally. Here, the authors use ultra-fast fMRI to show that humans preplay anticipated visual sequences in the primary visual cortex and that this preplay correlates with faster detection of the stimuli.

Matthias Ekman
Peter Kok
Floris P. de Lange

ResearchOpen Access23 May 2017

Nature Communications

Volume: 8, P: 1-9

Exome sequencing of 20,979 individuals with epilepsy reveals shared and distinct ultra-rare genetic risk across disorder subtypes

In this largest whole-exome sequencing study of epilepsies to date, the Epi25 Collaborative identified extremely rare variants that confer risk for diverse epilepsy subtypes, highlighting roles in synaptic transmission and neuronal excitability.

Siwei Chen
Bassel W. Abou-Khalil
Samuel F. Berkovic

Research03 Oct 2024

Nature Neuroscience

Volume: 27, P: 1864-1879

Temperature extremes of 2022 reduced carbon uptake by forests in Europe

Heat and moisture stress can reduce carbon uptake by forests. Here, the authors quantify this effect for the extreme 2022 European summer drought. The widespread reduction of photosynthesis exceeded the large local carbon release by intense fires.

Auke M. van der Woude
Wouter Peters
Ingrid T. Luijkx

ResearchOpen Access06 Oct 2023

Nature Communications

Volume: 14, P: 1-11

Accelerated lysine metabolism conveys kidney protection in salt-sensitive hypertension

Kidney metabolism in disease is important but not well understood. Here, using isotope-guided metabolomics, the authors show that lysine’s metabolic activity conveys kidney protection in hypertension through accelerated metabolism and physiological effects on tubular function.

Markus M. Rinschen
Oleg Palygin
Alexander Staruschenko

ResearchOpen Access14 Jul 2022

Nature Communications

Volume: 13, P: 1-17

Sister chromatid exchanges induced by perturbed replication can form independently of BRCA1, BRCA2 and RAD51

Sister chromatid exchanges (SCEs) are considered to be products of homologous recombination repair. The authors show that SCEs can arise independently of homologous recombination due to processing of replication intermediates during mitosis.

Anne Margriet Heijink
Colin Stok
Marcel A. T. M. van Vugt

ResearchOpen Access07 Nov 2022

Nature Communications

Volume: 13, P: 1-16

Annotating Whole Genome Sequencing in COSMIC (The Catalogue of Somatic Mutations in Cancer)

D Breare
M R Stratton
M Jia

MultimediaOpen Access27 Oct 2010

Nature Precedings

P: 1

Immune evasion by a staphylococcal complement inhibitor that acts on C3 convertases

Suzan H M Rooijakkers
Maartje Ruyken
Jos A G van Strijp

Research07 Aug 2005

Nature Immunology

Volume: 6, P: 920-927

Publisher Correction: Reference component analysis of single-cell transcriptomes elucidates cellular heterogeneity in human colorectal tumors

Huipeng Li
Elise T. Courtois
Shyam Prabhakar

Amendments and Corrections19 Dec 2022

Nature Genetics

Volume: 55, P: 166

Integrating multiple genomic technologies to investigate an outbreak of carbapenemase-producing Enterobacter hormaechei

Antibiotic-resistant bacteria are an urgent threat to human health. Here, Roberts et al. characterise and monitor an ongoing hospital outbreak of carbapenemase-producing Enterobacter hormaechei by integrating several technologies for whole-genome sequencing and shotgun metagenomics.

Leah W. Roberts
Patrick N. A. Harris
Scott A. Beatson

ResearchOpen Access24 Jan 2020

Nature Communications

Volume: 11, P: 1-11

Chirality of nanophotonic waveguide with embedded quantum emitter for unidirectional spin transfer

Scalable quantum technologies require efficient conversion between qubits stored in solid-state systems and flying photonic qubits. Here, the authors demonstrate that the electromagnetic field chirality of a photonic waveguide leads to unidirectional emission from an embedded quantum dot emitter.

R. J. Coles
D. M. Price
M. N. Makhonin

ResearchOpen Access31 Mar 2016

Nature Communications

Volume: 7, P: 1-7

Exciton–polariton light–semiconductor coupling effects

H. M. Gibbs
G. Khitrova
S. W. Koch

Reviews06 Mar 2011

Nature Photonics

Volume: 5, P: 273

Observational evidence for active dust storms on Titan at equinox

Saturn’s moon Titan may have an active dust cycle in equatorial regions driven by storm winds, Cassini observations consistent with dust suspension in Titan’s atmosphere suggest.

S. Rodriguez
S. Le Mouélic
P. D. Nicholson

Research24 Sept 2018

Nature Geoscience

Volume: 11, P: 727-732

Hypoallergenic diet may control refractory epilepsy in allergic children: A quasi experimental study

H. Gorjipour
S. Darougar
M. R. Sohrabi

ResearchOpen Access03 May 2019

Scientific Reports

Volume: 9, P: 1-7

Subjective signal strength distinguishes reality from imagination

How humans distinguish perception from mental imagery is not well understood. Here, the authors show that reality judgements are based on the intensity of a mixture of imagined and real signals.

Nadine Dijkstra
Stephen M. Fleming

ResearchOpen Access23 Mar 2023

Nature Communications

Volume: 14, P: 1-11

Pyruvate Carboxylase Deficiency: A Benign Variant with Normal Development

R N Van Coster
P M Fernhoff
D C De Vivo

Research01 Jul 1991

Pediatric Research

Volume: 30, P: 1-4

Author Correction: Tryptophan depletion results in tryptophan-to-phenylalanine substitutants

Abhijeet Pataskar
Julien Champagne
Reuven Agami

Amendments and CorrectionsOpen Access15 Jul 2022

Nature

Volume: 608, P: E20

Mutations in a human homologue of Drosophila crumbs cause retinitis pigmentosa (RP12)

Anneke I. den Hollander
Jacoline B. ten Brink
Arthur A.B. Bergen

Research01 Oct 1999

Nature Genetics

Volume: 23, P: 217-221

AMPA receptor GluA2 subunit defects are a cause of neurodevelopmental disorders

Genetic variants in ionotropic glutamate receptors have been implicated in neurodevelopmental disorders. Here, the authors report heterozygous de novo mutations in the GRIA2 gene in 28 individuals with intellectual disability and neurodevelopmental abnormalities associated with reduced Ca²⁺ transport and AMPAR currents.”

Vincenzo Salpietro
Christine L. Dixon
Henry Houlden

ResearchOpen Access12 Jul 2019

Nature Communications

Volume: 10, P: 1-16

Interleukin-13 receptor alpha 2 cooperates with EGFRvIII signaling to promote glioblastoma multiforme

Interleukin-13 receptor alpha 2 is highly expressed in glioblastoma multiforme but its role in this malignancy is unclear. Here the authors show that this receptor interacts with mutant EGFR, stimulating its kinase activity, thus inducing proliferation.

Jennifer P. Newman
Grace Y. Wang
Paula Y. P. Lam

ResearchOpen Access04 Dec 2017

Nature Communications

Volume: 8, P: 1-17

Serum Bile Acids in Newborns and Children

L Barbara
R Lazzari
E Roda

Research01 Nov 1980

Pediatric Research

Volume: 14, P: 1222-1225

Non-MHC antigens and their relative resistance to immunosuppression after corneal transplantation

Susan M Nicholls
Benjamin A Bradley
David L Easty

Research01 Mar 1995

Eye

Volume: 9, P: 208-214

Reactivity to human papillomavirus type 16 L1 virus-like particles in sera from patients with genital cancer and patients with carcinomas at five different extragenital sites

G J J Van Doornum
C M Korse
J Dillner

ResearchOpen Access01 Apr 2003

British Journal of Cancer

Volume: 88, P: 1095-1100

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