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Showing 1–19 of 19 results

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Author Correction: Consistent success in life-supporting porcine cardiac xenotransplantation

Matthias Längin
Tanja Mayr
Jan-Michael Abicht
Amendments and Corrections03 Apr 2019
Nature

Volume: 568, P: E7
Microbial metabolite drives ageing-related clonal haematopoiesis via ALPK1

ADP-heptose binds to ALPK1, triggering transcriptional reprogramming and NF-κB activation, endowing pre-leukaemic cells with a competitive advantage due to excessive clonal proliferation.

Puneet Agarwal
Avery Sampson
Daniel T. Starczynowski
ResearchOpen Access23 Apr 2025
Nature

Volume: 642, P: 201-211
Modulation of the clonal burden in patients with lower-risk myelodysplastic neoplasms treated with imetelstat

Valeria Santini
Amer M. Zeidan
Uwe Platzbecker
ResearchOpen Access12 Jan 2026
Leukemia

P: 1-13
Characterization of soluble E-cadherin as a disease marker in gastric cancer patients

J Gofuku
H Shiozaki
M Monden
Research01 Oct 1998
British Journal of Cancer

Volume: 78, P: 1095-1101
Soluble E-cadherin fragments increased in circulation of cancer patients

M Katayama
S Hirai
I Kato
Research01 Mar 1994
British Journal of Cancer

Volume: 69, P: 580-585
Urinary laminin fragments as a tumour marker potentially reflecting basement membrane destruction

M Katayama
K Kamihagi
I Kato
Research01 Apr 1992
British Journal of Cancer

Volume: 65, P: 509-514
Characterization of E1 enzyme dependencies in mutant-UBA1 human cells reveals UBA6 as a novel therapeutic target in VEXAS syndrome

Courtnee A. Clough
Claire Cunningham
Daniel Starczynowski
ResearchOpen Access30 Jun 2025
Leukemia

Volume: 39, P: 1997-2009
Automated real-world data integration improves cancer outcome prediction

A study generates a clinicogenomics dataset resource, MSK-CHORD, that combines natural language processing-derived clinical annotations with patient medical data from various sources to improve models of cancer outcome.

Justin Jee
Christopher Fong
Xinran Bi
ResearchOpen Access06 Nov 2024
Nature

Volume: 636, P: 728-736
Consistent success in life-supporting porcine cardiac xenotransplantation

α1,3-galactosyltransferase-knockout pig hearts that express human CD46 and human thrombomodulin require non-ischaemic preservation with continuous perfusion and post-transplantation growth control to ensure long-term orthotopic function of the xenograft in baboons.

Matthias Längin
Tanja Mayr
Jan-Michael Abicht
Research05 Dec 2018
Nature

Volume: 564, P: 430-433
T cells specific for α-myosin drive immunotherapy-related myocarditis

Cytotoxic CD8⁺ T cells specific for α-myosin are identified as pivotal players in myocarditis associated with immune checkpoint inhibitor anticancer therapies.

Margaret L. Axelrod
Wouter C. Meijers
Justin M. Balko
Research16 Nov 2022
Nature

Volume: 611, P: 818-826
Somatic gene editing ameliorates skeletal and cardiac muscle failure in pig and human models of Duchenne muscular dystrophy

CRISPR–Cas9-mediated gene editing restores dystrophin expression in both pig and human induced pluripotent stem cell models of Duchenne muscular dystrophy, with beneficial effects on skeletal muscle and cardiac function.

A. Moretti
L. Fonteyne
C. Kupatt
Research27 Jan 2020
Nature Medicine

Volume: 26, P: 207-214
Development of Calcium Channels in Gastric Smooth Muscle

P E Hyman
M G Martin
W J Snape Jr.
Research01 Jun 1989
Pediatric Research

Volume: 25, P: 600-604
DDX41 haploinsufficiency causes inefficient hematopoiesis under stress and cooperates with p53 mutations to cause hematologic malignancy

Emily Stepanchick
Andrew Wilson
Timothy M. Chlon
ResearchOpen Access27 Jun 2024
Leukemia

Volume: 38, P: 1787-1798
Effect of prior therapy on the clinical activity of imetelstat in patients with transfusion-dependent, ESA-relapsed or -refractory/-ineligible LR-MDS

Rami S. Komrokji
Valeria Santini
Uwe Platzbecker
CorrespondenceOpen Access31 Dec 2025
Blood Cancer Journal

Volume: 15, P: 1-4
The deubiquitinase USP15 modulates cellular redox and is a therapeutic target in acute myeloid leukemia

Madeline Niederkorn
Chiharu Ishikawa
Daniel T. Starczynowski
ResearchOpen Access31 Aug 2021
Leukemia

Volume: 36, P: 438-451
Preclinical mouse models of immune checkpoint inhibitor-associated myocarditis

Fankhauser et al. provide an in-depth review of preclinical mouse models used to study immune checkpoint inhibitor-associated myocarditis (ICI-myocarditis). They discuss potential improvements to the field that could, in the future, strengthen our understanding of ICI-myocarditis.

Reilly G. Fankhauser
Douglas B. Johnson
Justin M. Balko
Reviews07 May 2025
Nature Cardiovascular Research

Volume: 4, P: 526-538
Finding consistency in classifications of myeloid neoplasms: a perspective on behalf of the International Workshop for Myelodysplastic Syndromes

Amer M. Zeidan
Jan Philipp Bewersdorf
Valeria Santini
Correspondence20 Oct 2022
Leukemia

Volume: 36, P: 2939-2946
Molecular characterization of newly diagnosed acute myeloid leukemia patients aged 60 years or older: a report from the Beat AML clinical trial

Fieke W. Hoff
Ying Huang
Yazan F. Madanat
CorrespondenceOpen Access03 Apr 2025
Blood Cancer Journal

Volume: 15, P: 1-5
Differences in classification schemata for myelodysplastic/myeloproliferative overlap neoplasms

Mrinal M. Patnaik
Amer M. Zeidan
John M. Bennett
Correspondence05 Nov 2022
Leukemia

Volume: 36, P: 2934-2938