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Showing 1–3 of 3 results
Advanced filters: Author: M. Lagator Clear advanced filters
  • Transcription rates are regulated by the interactions between RNA polymerase, sigma factor, and promoter DNA sequences in bacteria. Here the authors combine massively parallel experiments & machine learning to develop a predictive biophysical model of transcription, validated across 22132 bacterial promoters, and apply it to the design and debugging of genetic circuits.

    • Travis L. LaFleur
    • Ayaan Hossain
    • Howard M. Salis
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-15
  • Experimental evolution in engineered Escherichia coli shows that amplification-mediated gene expression tuning, resulting from intrinsic instability of copy-number mutations, is a mechanism of gene expression regulation in fluctuating environments.

    • I. Tomanek
    • R. Grah
    • C. C. Guet
    Research
    Nature Ecology & Evolution
    Volume: 4, P: 612-625
  • Up to 40% of the ocean’s fixed nitrogen is lost in oxygen minimum zones (OMZs) by anammox, but despite the importance of this process, nitrogen loss patterns in OMZs are difficult to predict. Here the authors show that ammonium release from small particles is a major control of anammox in the Peruvian OMZ.

    • Clarissa Karthäuser
    • Soeren Ahmerkamp
    • Marcel M. M. Kuypers
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-12