Opioid-induced respiratory depression can be treated with intranasal (IN) or intramuscular (IM) naloxone. Here the authors report a randomized, crossover, open-label trial showing that lower number of IM doses are required for full reversal of breathing following fentanyl-induced apnea by comparison to IN doses.
- Maarten A. van Lemmen
- Monique van Velzen
- Rutger M. van der Schrier
