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Showing 1–3 of 3 results
Advanced filters: Author: Madelene Lindqvist Clear advanced filters

  • CD8+ T cell responses have been associated with control of HIV replication, but the role of CD4+ T cells in protecting against this virus is unclear. In an analysis of HLA class II–restricted CD4+ T cell responses in HIV-infected individuals, Hendrik Streeck and his colleagues now report that certain HLA-DRB1 variants are associated with low viremia and can present a wide breadth of peptides, suggesting that CD4+ T cell responses in infected individuals may help control HIV.

    • Srinika Ranasinghe
    • Sam Cutler
    • Hendrik Streeck
    Research
    Nature Medicine
    Volume: 19, P: 930-933

  • Flow cytometry allows high-throughput analysis of multiple proteins in individual cells, but relies on availability of antibodies. Here Porichis et al.report a sensitive method for multi-parameter flow cytometric and imaging detection of proteins together with mRNA or miRNA at the single-cell level.

    • Filippos Porichis
    • Meghan G. Hart
    • Daniel E. Kaufmann
    Research
    Nature Communications
    Volume: 5, P: 1-12