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Showing 1–4 of 4 results
Advanced filters: Author: Maelenn Chevreuil Clear advanced filters

  • Chromosome ends must be protected from fusion by NHEJ despite Ku binding to telomeres. Here, the authors show that at telomeres yeast Rap1 inhibits Ku’s translocation on DNA, preventing NHEJ and protecting telomeres without displacing Ku.

    • Stefano Mattarocci
    • Sonia Baconnais
    • Stéphane Marcand
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-13

  • Tecovirimat forces dimerization of the poxvirus phospholipase F13 blocking virus spread. Clinical monkeypox virus strains resistant to tecovirimat show mutations in the F13 dimer interface.

    • Riccardo Vernuccio
    • Alejandro Martínez León
    • Pablo Guardado-Calvo
    ResearchOpen Access
    Nature Microbiology
    Volume: 10, P: 734-748

  • Here the authors present the structure of Replication Protein A (RPA) in Archaea. The RPA structure from P. abyssi has been determined in presence and absence of DNA, providing insights into the evolution of this replication factor in eukaryotes

    • Clément Madru
    • Markel Martínez-Carranza
    • Ludovic Sauguet
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-14

  • The mechanism by which virus capsules assemble around RNA to package their genetic material is not clear. Here, the authors observed the assembly of the cowpea chlorotic mottle virus capsid around viral RNA or poly(styrene sulfonic acid) using time-resolved small-angle X-ray scattering measurements.

    • Maelenn Chevreuil
    • Didier Law-Hine
    • Guillaume Tresset
    ResearchOpen Access
    Nature Communications
    Volume: 9, P: 1-9