Advanced search

Filter By:

Journal Check one or more journals to show results from those journals only.

Choose more journals

Article type Check one or more article types to show results from those article types only.
Subject Check one or more subjects to show results from those subjects only.
Date Choose a date option to show results from those dates only.

Custom date range

Clear all filters
Sort by:
Showing 1–4 of 4 results
Advanced filters: Author: Magdalena Bogus Clear advanced filters

  • We uncover key processes of the genomic evolution of small cell lung cancer under therapy, identify the common ancestor as the source of clonal diversity at relapse and show central genomic patterns associated with drug response.

    • Julie George
    • Lukas Maas
    • Roman K. Thomas
    ResearchOpen Access
    Nature
    Volume: 627, P: 880-889

  • Pulmonary carcinoids account for about 2% of pulmonary neoplasms. Here, the authors carry out gene copy number analysis, genome/exome, and transcriptome sequencing of pulmonary carcinoids and identify frequent mutations in chromatin-remodelling genes that can drive tumorigenesis in these tumours.

    • Lynnette Fernandez-Cuesta
    • Martin Peifer
    • Roman K. Thomas
    Research
    Nature Communications
    Volume: 5, P: 1-7

  • Genomic sequencing of 110 human small cell lung cancers identifies genomic signatures including nearly ubiquitous bi-allelic inactivation of TP53 and RB1, a role for NOTCH family genes, and somatic rearrangements that create an oncogenic version of TP73.

    • Julie George
    • Jing Shan Lim
    • Roman K. Thomas
    Research
    Nature
    Volume: 524, P: 47-53

  • The molecular nature of large-cell neuroendocrine lung carcinomas (LCNEC) has remained unclear. Here, the authors show LCNECs represent a distinct transcriptional subgroup among lung cancers and comprise two molecular subgroups, type I (TP53 and STK11/KEAP1 alterations) and type II (TP53 and RB1 inactivation).

    • Julie George
    • Vonn Walter
    • Roman K. Thomas
    ResearchOpen Access
    Nature Communications
    Volume: 9, P: 1-13