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Showing 1–3 of 3 results
Advanced filters: Author: Magnus Gottfredsson Clear advanced filters

  • This study presents the genomes of 2,101 emm28 Streptococcus pyogenes invasive strains, of which 492 were transcriptionally profiled, and 50 were assessed for virulence. GWAS, eQTL analysis, and study of isogenic mutant strains identified an intergenic region that alters global transcript profiles and bacterial virulence.

    • Priyanka Kachroo
    • Jesus M. Eraso
    • James M. Musser
    Research
    Nature Genetics
    Volume: 51, P: 548-559

  • Holm, Ivarsdottir, Olafsdottir et al. compare symptoms and physical measures between Icelanders post SARS-CoV-2 infection with uninfected controls. From reported symptoms, they estimate the prevalence of long COVID as 7% at a median of 8 months after infection, while objective differences between cases and controls in the physical measures were few.

    • Hilma Holm
    • Erna V. Ivarsdottir
    • Kari Stefansson
    ResearchOpen Access
    Communications Medicine
    Volume: 3, P: 1-13

  • Ingileif Jonsdottir, Kari Stefansson and colleagues show that variants in the HLA class II region contribute to tuberculosis risk in populations of European ancestry. They propose that the associated variants influence disease risk by altering expression of HLA class II molecules presenting protective M. tuberculosis antigens to T cells.

    • Gardar Sveinbjornsson
    • Daniel F Gudbjartsson
    • Kari Stefansson
    Research
    Nature Genetics
    Volume: 48, P: 318-322