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Showing 1–2 of 2 results
Advanced filters: Author: Maikel Castellano-Pozo Clear advanced filters

  • The study shows that DNA double-strand break repair follows a circadian rhythm: homologous recombination peaks in the morning and declines by evening. CRY1 regulates CCAR2 to modulate this cycle, linking daily timing to genomic stability and cancer therapy response.

    • Amador Romero-Franco
    • Cintia Checa-Rodríguez
    • Pablo Huertas
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-18

  • Meiosis-specific cohesins and the synaptonemal complex are essential for meiotic chromosome structure and function. Here the authors show that continued surveillance of these chromosome structures controls meiotic progression by regulating CHK-2, a master regulator of pairing and recombination.

    • Maikel Castellano-Pozo
    • Sarai Pacheco
    • Enrique Martinez-Perez
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-16