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Showing 1–4 of 4 results
Advanced filters: Author: Mailin-Christin Manke Clear advanced filters

  • de Jonckheere, Kollotzek, et al. report a quantitative proteomic and lipidomic map of different stages of megakaryopoiesis and find an anionic lipid membrane remodeling and concomitant relocalization of the CKIP-1/CK2α complex to the plasma membrane of maturing megakaryocytes, which appear to be essential for sufficient platelet biogenesis.

    • Bianca de Jonckheere
    • Ferdinand Kollotzek
    • Robert Ahrends
    ResearchOpen Access
    Nature Cardiovascular Research
    Volume: 2, P: 835-852

  • Targeted mass spectrometry enables reproducible and accurate lipid quantification but dedicated software tools to develop targeted lipidomics assays are lacking. Here, the authors develop a targeted lipidomics workbench and lipid knowledgebase for the streamlined generation of targeted assays.

    • Bing Peng
    • Dominik Kopczynski
    • Robert Ahrends
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-14

  • ACKR3 is a critical regulator of platelet-mediated thrombosis and organ injury following ischemia/reperfusion. Platelet ACKR3 surface expression is independently associated with all-cause mortality in patients with cardiovascular diseases.

    • Anne-Katrin Rohlfing
    • Kyra Kolb
    • Meinrad Gawaz
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-20