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Showing 1–4 of 4 results
Advanced filters: Author: Maja Illig Clear advanced filters

  • Contractile rings are formed from cytoskeletal filaments, specific crosslinkers and motor proteins during cell division. Here, authors form micron-scale contractile DNA rings from DNA nanotubes and synthetic crosslinkers, with both simulations and experiments showing ring contraction without motor proteins, offering a potential first step towards synthetic cell division machinery.

    • Maja Illig
    • Kevin Jahnke
    • Kerstin Göpfrich
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-12

  • Reduced glomerular filtration rate (eGFR) is a hallmark of chronic kidney disease. Here, Pattaro et al. conduct a meta-analysis to discover several new loci associated with variation in eGFR and find that genes associated with eGFR loci often encode proteins potentially related to kidney development.

    • Cristian Pattaro
    • Alexander Teumer
    • Caroline S. Fox
    ResearchOpen Access
    Nature Communications
    Volume: 7, P: 1-19

  • This study introduces RNA origami nanotubes as self-assembling cytoskeleton mimics for synthetic cells. Expressed in vesicles from DNA templates, these RNA structures reach micrometre lengths, deform membranes and exhibit different phenotypes.

    • Mai P. Tran
    • Taniya Chakraborty
    • Kerstin Göpfrich
    ResearchOpen Access
    Nature Nanotechnology
    Volume: 20, P: 664-671