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Showing 1–4 of 4 results
Advanced filters: Author: Major L Cohn Clear advanced filters

  • The quest for a practical total artificial heart (TAH) stems from the large number of patients with advanced heart failure, and the limited number of donor hearts available for transplantation. In this Perspectives article, Cohn et al. give their expert insight into the development of TAHs over the past 50 years. They describe the evolution from positive-displacement, pulsatile pumps to continuous-flow devices, and give their opinion on the most promising avenues for future innovation.

    • William E. Cohn
    • Daniel L. Timms
    • O. H. Frazier
    Reviews
    Nature Reviews Cardiology
    Volume: 12, P: 609-617

  • Prosthetic aortic valves are often required for patients with aortic stenosis. The optimal choice of valve in middle-aged patients is not clear and the available options all have drawbacks. Patient choice is the most important factor in deciding which valve to use, with biological valves increasingly favored over mechanical valves. The authors of this Review present the various prosthetic aortic valves currently in use and discuss the implications of prosthesis selection in this group of patients.

    • Joanna Chikwe
    • Farzan Filsoufi
    • Alain F. Carpentier
    Reviews
    Nature Reviews Cardiology
    Volume: 7, P: 711-719