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Showing 1–2 of 2 results
Advanced filters: Author: Maksim M. Karasev Clear advanced filters

  • Precise control of covalent protein binding and cleavage in live cells is needed but technically challenging. Here, the authors developed a photoswitchable intein that enables efficient, low background, light-controlled manipulation of covalent bonds in polypeptides.

    • Mikhail Baloban
    • Kyrylo Yu. Manoilov
    • Daria M. Shcherbakova
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-14

  • Optogenetic approaches to control protein-protein interactions usually require overexpression of the target proteins. Here the authors integrate intrabodies into near-infrared- and blue-light activatable optogenetic tools to control endogenous proteins in mammalian cells.

    • Taras A. Redchuk
    • Maksim M. Karasev
    • Vladislav V. Verkhusha
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-12