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Showing 1–1 of 1 results
Advanced filters: Author: Malcom H. A. Rustin Clear advanced filters

  • Senescent cells increase with ageing and may cause inflammatory conditions, but how this accumulation is mediated is still unclear. Here the authors show that senescent cells express HLA-E to suppress NKG2A-mediated natural killer and CD8 T cell activation to avoid targeted elimination, while blocking NKG2A helps promote immunity against senescent cells.

    • Branca I. Pereira
    • Oliver P. Devine
    • Arne N. Akbar
    ResearchOpen Access
    Nature Communications
    Volume: 10, P: 1-13