Nature Search

Mapping the human genetic architecture of COVID-19

A global network of researchers was formed to investigate the role of human genetics in SARS-CoV-2 infection and COVID-19 severity; this paper reports 13 genome-wide significant loci and potentially actionable mechanisms in response to infection.

Mari E. K. Niemi
Juha Karjalainen
Chloe Donohue
ResearchOpen Access08 Jul 2021
Nature

Volume: 600, P: 472-477
Self-organized lasers from reconfigurable colloidal assemblies

Experiments inspired by the behaviour of active matter show that an external optical stimulus can spatially reconfigure colloidal random lasers and continuously tune their lasing threshold.

Manish Trivedi
Dhruv Saxena
Giorgio Volpe
Research14 Jul 2022
Nature Physics

Volume: 18, P: 939-944
Towards causal inference-based antidepressant selection with brain and blood biomarkers

Milica Barac
Caroline W. Grant
Madhukar H. Trivedi
ResearchOpen Access05 Sept 2025
Neuropsychopharmacology

Volume: 51, P: 622-630
A second update on mapping the human genetic architecture of COVID-19

Masahiro Kanai
Shea J. Andrews
Matthew Solomonson
ResearchOpen Access06 Sept 2023
Nature

Volume: 621, P: E7-E26
An electroencephalographic signature predicts antidepressant response in major depression

The efficacy of an antidepressant is predicted from an EEG signature.

Wei Wu
Yu Zhang
Amit Etkin
Research10 Feb 2020
Nature Biotechnology

Volume: 38, P: 439-447
Environmental memory boosts group formation of clueless individuals

Indirect coordination among individuals through the environment typically requires some basic levels of communication and information processing. Dias et al. introduce a coordination mechanism that emerges in a population of clueless individuals, facilitated by environmental memory, culminating in group formation.

Cristóvão S. Dias
Manish Trivedi
Giorgio Volpe
ResearchOpen Access13 Nov 2023
Nature Communications

Volume: 14, P: 1-11
Fibroblast growth factor 21 (FGF21) is increased in MDD and interacts with body mass index (BMI) to affect depression trajectory

Brittany L. Mason
Abu Minhajuddin
Madhukar H. Trivedi
ResearchOpen Access11 Jan 2022
Translational Psychiatry

Volume: 12, P: 1-6
Large-scale phenotyping of patients with long COVID post-hospitalization reveals mechanistic subtypes of disease

Openshaw and colleagues find myeloid inflammation and complement activation signatures in patients with long COVID who were previously hospitalized.

Felicity Liew
Claudia Efstathiou
J. Eunice Zhang
ResearchOpen Access08 Apr 2024
Nature Immunology

Volume: 25, P: 607-621
Brain regulation of emotional conflict predicts antidepressant treatment response for depression

Fonzo et al. found that brain activity during a form of emotional regulation predicted how well individuals with depression would respond to a common antidepressant. Brain function assays may herald a new era of precision medicine in psychiatry.

Gregory A. Fonzo
Amit Etkin
Madhukar H. Trivedi
Research23 Sept 2019
Nature Human Behaviour

Volume: 3, P: 1319-1331
Whole-genome sequencing reveals host factors underlying critical COVID-19

Whole-genome sequencing, transcriptome-wide association and fine-mapping analyses in over 7,000 individuals with critical COVID-19 are used to identify 16 independent variants that are associated with severe illness in COVID-19.

Athanasios Kousathanas
Erola Pairo-Castineira
J. Kenneth Baillie
ResearchOpen Access07 Mar 2022
Nature

Volume: 607, P: 97-103
Leveraging the microbiome to understand clinical heterogeneity in depression: findings from the T-RAD study

Cherise R. Chin Fatt
Sarah Asbury
Madhukar H. Trivedi
ResearchOpen Access28 Apr 2023
Translational Psychiatry

Volume: 13, P: 1-11
Identifying novel mechanisms and treatment targets for irritability and aggression in psychiatric disorders

Manish Kumar Jha
Madhukar H. Trivedi
Research20 Sept 2021
Neuropsychopharmacology

Volume: 47, P: 420-421
Dysregulation of mitochondrial dynamics, mitophagy and apoptosis in major depressive disorder: Does inflammation play a role?

Giselli Scaini
Brittany L. Mason
João Quevedo
Research14 Oct 2021
Molecular Psychiatry

Volume: 27, P: 1095-1102
Antimicrobial efficacy of Odontopaste in endodontics: a systematic review

Rachael Kendell-Wall
Jennifer-Thuy Nguyen
Rodrigo Rodrigues Amaral
ResearchOpen Access27 Mar 2024
Evidence-Based Dentistry

Volume: 25, P: 166
HBeAg-induced miR-106b promotes cell growth by targeting the retinoblastoma gene

Jasmine Samal
Manish Kandpal
Perumal Vivekanandan
ResearchOpen Access30 Oct 2017
Scientific Reports

Volume: 7, P: 1-10
Association between irritability and suicidal ideation in three clinical trials of adults with major depressive disorder

Manish K. Jha
Abu Minhajuddin
Madhukar H. Trivedi
Research14 Jul 2020
Neuropsychopharmacology

Volume: 45, P: 2147-2154
Do baseline sub-threshold hypomanic symptoms affect acute-phase antidepressant outcome in outpatients with major depressive disorder? Preliminary findings from the randomized CO-MED trial

Manish K. Jha
Ashley L. Malchow
Madhukar H. Trivedi
Research15 Aug 2018
Neuropsychopharmacology

Volume: 43, P: 2197-2203
An early warning system for emerging SARS-CoV-2 variants

Global sequencing and surveillance capacity for SARS-CoV-2 must be strengthened and combined with multidisciplinary studies of infectivity, virulence and immune escape, in order to track the unpredictable evolution of the ongoing COVID-19 pandemic.

Lorenzo Subissi
Anne von Gottberg
Anurag Agrawal
Comments & Opinion30 May 2022
Nature Medicine

Volume: 28, P: 1110-1115
Correction: Double-blind, placebo-controlled, dose-ranging trial of intravenous ketamine as adjunctive therapy in treatment-resistant depression (TRD)

Maurizio Fava
Marlene P. Freeman
George I. Papakostas
Amendments and Corrections07 Jan 2019
Molecular Psychiatry

Volume: 25, P: 1604
Comparative effectiveness research trial for antidepressant incomplete and non-responders with treatment resistant depression (ASCERTAIN-TRD) a randomized clinical trial

George I. Papakostas
Madhukar H. Trivedi
Maurizio Fava
ResearchOpen Access07 Mar 2024
Molecular Psychiatry

Volume: 29, P: 2287-2295
Double-blind, placebo-controlled, dose-ranging trial of intravenous ketamine as adjunctive therapy in treatment-resistant depression (TRD)

Maurizio Fava
Marlene P. Freeman
George I. Papakostas
Research03 Oct 2018
Molecular Psychiatry

Volume: 25, P: 1592-1603
Silencing of sterol glycosyltransferases modulates the withanolide biosynthesis and leads to compromised basal immunity of Withania somnifera

Gaurav Singh
Manish Tiwari
Pratibha Misra
ResearchOpen Access05 May 2016
Scientific Reports

Volume: 6, P: 1-13
Expression of OsMATE1 and OsMATE2 alters development, stress responses and pathogen susceptibility in Arabidopsis

Manish Tiwari
Deepika Sharma
Prabodh Kumar Trivedi
ResearchOpen Access04 Feb 2014
Scientific Reports

Volume: 4, P: 1-12

Search

Mapping the human genetic architecture of COVID-19

Self-organized lasers from reconfigurable colloidal assemblies

Towards causal inference-based antidepressant selection with brain and blood biomarkers

A second update on mapping the human genetic architecture of COVID-19

An electroencephalographic signature predicts antidepressant response in major depression

Environmental memory boosts group formation of clueless individuals

Fibroblast growth factor 21 (FGF21) is increased in MDD and interacts with body mass index (BMI) to affect depression trajectory

Large-scale phenotyping of patients with long COVID post-hospitalization reveals mechanistic subtypes of disease

Brain regulation of emotional conflict predicts antidepressant treatment response for depression

Whole-genome sequencing reveals host factors underlying critical COVID-19

Leveraging the microbiome to understand clinical heterogeneity in depression: findings from the T-RAD study

Identifying novel mechanisms and treatment targets for irritability and aggression in psychiatric disorders

Dysregulation of mitochondrial dynamics, mitophagy and apoptosis in major depressive disorder: Does inflammation play a role?

Antimicrobial efficacy of Odontopaste in endodontics: a systematic review

HBeAg-induced miR-106b promotes cell growth by targeting the retinoblastoma gene

Association between irritability and suicidal ideation in three clinical trials of adults with major depressive disorder

Do baseline sub-threshold hypomanic symptoms affect acute-phase antidepressant outcome in outpatients with major depressive disorder? Preliminary findings from the randomized CO-MED trial

An early warning system for emerging SARS-CoV-2 variants

Correction: Double-blind, placebo-controlled, dose-ranging trial of intravenous ketamine as adjunctive therapy in treatment-resistant depression (TRD)

Comparative effectiveness research trial for antidepressant incomplete and non-responders with treatment resistant depression (ASCERTAIN-TRD) a randomized clinical trial

Double-blind, placebo-controlled, dose-ranging trial of intravenous ketamine as adjunctive therapy in treatment-resistant depression (TRD)

Silencing of sterol glycosyltransferases modulates the withanolide biosynthesis and leads to compromised basal immunity of Withania somnifera

Expression of OsMATE1 and OsMATE2 alters development, stress responses and pathogen susceptibility in Arabidopsis

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