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Showing 1–2 of 2 results
Advanced filters: Author: Manjuli R. Sharma Clear advanced filters

  • Translation within mitochondria is carried out by specialized mitoribosomes and translational factors. Here the authors describe cryo-EM structures of the human mitochondrial translation elongation factor G1 in complex with human mitoribosomes, revealing distinct mechanism that include conformational changes at the polypeptide exit tunnel.

    • Ravi Kiran Koripella
    • Manjuli R. Sharma
    • Rajendra K. Agrawal
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-11

  • Ribosomes are prime targets for antibiotics in pathogenic bacteria. Here, cryo-electron microscopy reveals features in the Borrelia burgdorferi ribosome that provide insights into ribosome evolution, dormancy, and antibiotic binding.

    • Manjuli R. Sharma
    • Swati R. Manjari
    • Nilesh K. Banavali
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-11