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Showing 1–2 of 2 results
Advanced filters: Author: Mansoore Esmaili Clear advanced filters

  • Site-specific endonucleases that exclusively cut single-stranded DNA have hitherto never been described and constitute a barrier to the development of ssDNA-based technologies. Here the authors identify and characterize a family of such enzymes that could be the basis of innovative molecular tools.

    • Martin Chenal
    • Alex Rivera-Millot
    • Frédéric J. Veyrier
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-15

  • The ‘N-end rule’ correlates the identity of the N-terminal residue of a protein to its in vivo half-life. A study has now shown that an N-terminal glycine can serve as a potent degradation signal, which reveals a novel branch of N terminus–dependent protein degradation.

    • Mohamed Eldeeb
    • Mansoore Esmaili
    • Richard Fahlman
    News & Views
    Nature Structural & Molecular Biology
    Volume: 26, P: 761-763