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Showing 1–1 of 1 results
Advanced filters: Author: Manuradhi Perera Clear advanced filters

  • GLIS3 mutations are associated with type 1, type 2, and neonatal diabetes. Here, the authors generate mono-hormonal glucose-responding pancreatic β-like cells in vitro and through a screen identify a drug that rescues pancreatic β-like cell death in GLIS3 mutants by inhibiting the abnormally activated TGFβ pathway.

    • Sadaf Amin
    • Brandoch Cook
    • Shuibing Chen
    ResearchOpen Access
    Nature Communications
    Volume: 9, P: 1-12