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Showing 1–2 of 2 results
Advanced filters: Author: Manyin Wu Clear advanced filters
  • Proinflammatory macrophages mediate protective immunity but also contribute to inflammatory diseases. Here the authors show that the E3 ligase, MDM2, induces nitric oxide from macrophage, potentially triggering the s-nitrosylation and activation of HIF-1α for the production of inflammatory cytokines, to protect mice from sepsis but aggravate obesity-induced inflammation.

    • Kelvin Ka-lok Wu
    • Xiaofan Xu
    • Kenneth King-yip Cheng
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-21
  • roX (RNA on the X) are crucial for male development in Drosophila. Here, the authors propose a role for roX RNAs in regulating gene expression at specific autosomal loci, working in coordination with Polycomb repressive complexes (PRCs).

    • Jianjian Li
    • Shuyang Xu
    • Qing Ma
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-14