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Advanced filters: Author: Mara Mitstorfer Clear advanced filters

  • By performing a CAR-adapted base-editing screen of phosphatidylinositol-3-kinase delta (PI3Kδ, PIK3CD), Bucher et al. identify mutations affecting endogenous PI3K–AKT signaling that enhances CAR T cell antitumor potency.

    • Philip Bucher
    • Nadine Brückner
    • Josef Leibold
    ResearchOpen Access
    Nature Cancer
    Volume: 7, P: 368-383