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Showing 1–6 of 6 results
Advanced filters: Author: Marc Vervloet Clear advanced filters
  • Fibroblast growth factor 23 (FGF23) regulates phosphate homeostasis by modulating renal phosphate absorption, vitamin D metabolism and parathyroid hormone secretion. In this Review, Marc Vervloet discusses the role of FGF23 on phosphate regulation as well as its additional effects in the cardiovascular and immune systems.

    • Marc Vervloet
    Reviews
    Nature Reviews Nephrology
    Volume: 15, P: 109-120
  • Hyperphosphataemia is associated with poor clinical outcomes but strong evidence that targeting serum phosphate improves these outcomes is lacking. Here the authors discuss the role, regulation and management of serum phosphate in chronic kidney disease, including the efficacies of phosphate binder therapy and dietary interventions.

    • Marc G. Vervloet
    • Siren Sezer
    • Denis Fouque
    Reviews
    Nature Reviews Nephrology
    Volume: 13, P: 27-38
  • Patients with chronic kidney disease (CKD) are known to have increased all-cause and cardiovascular mortality. Of late, it has been recognized that these patients also have increased noncardiovascular mortality. Here, the authors discuss both cardiovascular and nonocardiovascular mortality in CKD, provide examples of traditional cardiovascular risk factors that also seem to be associated with noncardiovascular mortality, and summarize the potential pathophysiological mechanisms involved.

    • Dinanda J. de Jager
    • Marc G. Vervloet
    • Friedo W. Dekker
    Reviews
    Nature Reviews Nephrology
    Volume: 10, P: 208-214