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Showing 1–2 of 2 results
Advanced filters: Author: Marcel Grogg Clear advanced filters

  • Cyanophycin synthetase CphA1 polymerizes Asp and Arg into the nitrogen reserve polymer cyanophycin using two active sites. Sharon et al. show CphA1 has a cryptic 3rd active site that cleaves cyanophycin into primers for self-sufficient biosynthesis.

    • Itai Sharon
    • Sharon Pinus
    • T. Martin Schmeing
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-10

  • Structures of three cyanophycin synthetases reveal how the constituent glutathione synthetase and muramyl ligase-like domains cooperate to make cyanophycin, a poly-aspartate chain with arginine residues attached to the sidechains by isopeptide bonds.

    • Itai Sharon
    • Asfarul S. Haque
    • T. Martin Schmeing
    Research
    Nature Chemical Biology
    Volume: 17, P: 1101-1110